HitPredict

Interactor 1: NUP1 (P20676)
Nucleoporin NUP1 (Nuclear pore protein NUP1)
Gene: NUP1

Interactor 2: IMB5 (P53067)
Importin subunit beta-5 (114 kDa karyopherin) (Karyopherin subunit beta-5) (Karyopherin-114)
Gene: KAP114

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	15888545
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005635 - nuclear envelope GO:0005643 - nuclear pore GO:0006606 - protein import into nucleus GO:0006607 - NLS-bearing protein import into nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1076 Sc			1 1004
+	Hs
		312215 NU153_HUMAN (3-977): 5.82e-79: 285: 14.89		IPO7_HUMAN (1-1002): 0: 569: 13.62
+	Hs
		834599 NU153_HUMAN (3-977): 5.82e-79: 285: 14.89		IMB1_HUMAN (1-876): 4.04e-142: 448: 10.93
+	Hs
		834652 NU153_HUMAN (3-977): 5.82e-79: 285: 14.89		TNPO1_HUMAN (8-841): 4.95e-133: 425: 10.71
+	Hs
		155550 NU153_HUMAN (3-977): 5.82e-79: 285: 14.89		TNPO2_HUMAN (8-841): 2.41e-129: 415: 10.72
+	Sc
		595069 NUP1_YEAST (1-1076): 2e-160: 505: 100.00		SXM1_YEAST (3-938): 7.24e-40: 162: 12.91
+	Sc
		595042 NUP1_YEAST (1-1076): 2e-160: 505: 100.00		NMD5_YEAST (1-830): 3.08e-39: 160: 13.64
+	Hs
		727228 NU214_HUMAN (164-1040): 5.69e-09: 62.6: 14.85		XPO2_HUMAN (3-949): 5.99e-165: 511: 11.44
+	Hs
		1060869 P121A_HUMAN (51-1071): 1.05e-14: 81.4: 11.47		IMB1_HUMAN (1-876): 4.04e-142: 448: 10.93
+	Hs
		857978 NUP98_HUMAN (204-882): 2.45e-12: 73.8: 14.55		IMB1_HUMAN (1-876): 4.04e-142: 448: 10.93
+	Hs
		65042 P121C_HUMAN (234-1054): 1.09e-09: 64.9: 13.06		IMB1_HUMAN (1-876): 4.04e-142: 448: 10.93
+	Hs
		72728 B4DET5_HUMAN (258-1054): 9.4e-10: 64.9: 12.84		IMB1_HUMAN (1-876): 4.04e-142: 448: 10.93
+	Hs
		727254 NU214_HUMAN (164-1040): 5.69e-09: 62.6: 14.85		IMB1_HUMAN (1-876): 4.04e-142: 448: 10.93
+	Hs
		858024 NUP98_HUMAN (204-882): 2.45e-12: 73.8: 14.55		TNPO1_HUMAN (8-841): 4.95e-133: 425: 10.71
+	Hs
		155553 NUP98_HUMAN (204-882): 2.45e-12: 73.8: 14.55		TNPO2_HUMAN (8-841): 2.41e-129: 415: 10.72
+	Hs
		727300 NU214_HUMAN (164-1040): 5.69e-09: 62.6: 14.85		TNPO1_HUMAN (8-841): 4.95e-133: 425: 10.71
+	Xl
		1137359 NU153_XENLA (347-1043): 2.87e-11: 70.3: 15.26		Q5U4V0_XENLA (8-841): 1.48e-128: 413: 10.49
+	Sc
		691638 NUP2_YEAST (435-840): 1.31e-31: 135: 25.17		NMD5_YEAST (1-830): 3.08e-39: 160: 13.64
+	Sc
		774375 NU159_YEAST (347-936): 2.15e-17: 90.3: 14.33		SXM1_YEAST (3-938): 7.24e-40: 162: 12.91
+	Sc
		774353 NU159_YEAST (347-936): 2.15e-17: 90.3: 14.33		NMD5_YEAST (1-830): 3.08e-39: 160: 13.64
+	Sc
		541922 NSP1_YEAST (511-1032): 4.79e-13: 75.7: 16.10		SXM1_YEAST (3-938): 7.24e-40: 162: 12.91