HitPredict

Interactor 1: LMNB1 (P20700)
Lamin-B1
Gene: LMNB1

Interactor 2: NEST (P48681)
Nestin
Gene: NES

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.80	0.618

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Filament~Filament
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 586 Hs			1 1621
+	Hs
		531570 K2C5_HUMAN (4-391): 3.18e-123: 377: 23.74		K1H2_HUMAN (6-313): 1.75e-82: 281: 20.63
+	Hs
		280766 K2C6A_HUMAN (4-407): 1.22e-124: 380: 22.82		KRT36_HUMAN (6-313): 8.66e-80: 273: 20.56
+	Hs
		280773 K2C5_HUMAN (4-391): 3.18e-123: 377: 23.74		KRT36_HUMAN (6-313): 8.66e-80: 273: 20.56
+	Hs
		443325 LMNB1_HUMAN (1-586): 2.13e-71: 242: 100.00		VIME_HUMAN (8-343): 3.05e-118: 382: 28.32
+	Hs
		380475 K2C6B_HUMAN (4-407): 8.91e-87: 282: 21.85		K1H2_HUMAN (6-313): 1.75e-82: 281: 20.63
+	Hs
		280782 K2C6C_HUMAN (4-407): 3.4e-87: 283: 22.09		KRT36_HUMAN (6-313): 8.66e-80: 273: 20.56
+	Hs
		280767 K2C6B_HUMAN (4-407): 8.91e-87: 282: 21.85		KRT36_HUMAN (6-313): 8.66e-80: 273: 20.56
+	Hs
		1055185 K2C72_HUMAN (2-391): 2.63e-68: 231: 21.11		K1H2_HUMAN (6-313): 1.75e-82: 281: 20.63
+	Hs
		359446 LMNA_HUMAN (3-550): 3.87e-63: 221: 55.37		K2C6A_HUMAN (6-332): 1.03e-84: 291: 20.82
+	Hs
		280800 K2C71_HUMAN (4-391): 3.1e-69: 234: 19.95		KRT36_HUMAN (6-313): 8.66e-80: 273: 20.56
+	Hs
		280797 K2C72_HUMAN (2-391): 2.63e-68: 231: 21.11		KRT36_HUMAN (6-313): 8.66e-80: 273: 20.56
+	Hs
		280812 K2C73_HUMAN (2-391): 1.07e-53: 193: 19.70		KRT36_HUMAN (6-313): 8.66e-80: 273: 20.56
+	Hs
		280787 KRT83_HUMAN (54-390): 2.93e-51: 185: 19.88		KRT36_HUMAN (6-313): 8.66e-80: 273: 20.56
+	Mm
		821715 LMNA_MOUSE (3-580): 4.36e-63: 221: 53.37		Q6IFZ8_MOUSE (6-317): 6.8e-56: 206: 19.38
+	Hs
		943625 KRT83_HUMAN (54-390): 2.93e-51: 185: 19.88		KRT83_HUMAN (6-313): 2.92e-64: 229: 21.34
+	Mm
		821725 LMNA_MOUSE (3-580): 4.36e-63: 221: 53.37		MYH9_MOUSE (669-1518): 3.07e-31: 136: 9.52
+	Hs
		1061108 K2C72_HUMAN (2-391): 2.63e-68: 231: 21.11		NUMA1_HUMAN (818-1473): 5.43e-19: 96.5: 10.02
+	Hs
		1062052 K2C72_HUMAN (2-391): 2.63e-68: 231: 21.11		AINX_HUMAN (8-317): 2.29e-17: 89.4: 27.59
+	Hs
		359949 LMNA_HUMAN (3-550): 3.87e-63: 221: 55.37		NUMA1_HUMAN (818-1473): 5.43e-19: 96.5: 10.02
+	Hs
		569099 K2C73_HUMAN (2-391): 1.07e-53: 193: 19.70		DESM_HUMAN (8-316): 2.1e-14: 79.7: 25.47