HitPredict

Interactor 1: LMNB1 (P20700)
Lamin-B1
Gene: LMNB1

Interactor 2: NU153 (P49790)
Nuclear pore complex protein Nup153 (153 kDa nucleoporin) (Nucleoporin Nup153)
Gene: NUP153

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	34079125, 35271311
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005635 - nuclear envelope GO:0005654 - nucleoplasm GO:0016020 - membrane GO:0031965 - nuclear membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 586 Hs			1 1475
+	Hs
		359762 LMNA_HUMAN (3-550): 3.87e-63: 221: 55.37		NU153_HUMAN (1-1475): 2.98e-176: 568: 100.00
+	Hs
		359526 K2C6A_HUMAN (4-407): 1.22e-124: 380: 22.82		RNF31_HUMAN (545-922): 9.86e-47: 185: 15.72
+	Hs
		531618 K2C5_HUMAN (4-391): 3.18e-123: 377: 23.74		RNF31_HUMAN (545-922): 9.86e-47: 185: 15.72
+	Hs
		359543 K2C6A_HUMAN (4-407): 1.22e-124: 380: 22.82		ZRAN1_HUMAN (589-796): 5.46e-22: 105: 16.89
+	Hs
		531644 K2C5_HUMAN (4-391): 3.18e-123: 377: 23.74		ZRAN1_HUMAN (589-796): 5.46e-22: 105: 16.89
+	Hs
		595145 LMNB1_HUMAN (1-586): 2.13e-71: 242: 100.00		RBP2_HUMAN (573-1152): 6.9e-53: 207: 19.12
+	Hs
		359942 LMNA_HUMAN (3-550): 3.87e-63: 221: 55.37		MDC1_HUMAN (67-796): 3.59e-56: 217: 14.00
+	Hs
		359763 LMNA_HUMAN (3-550): 3.87e-63: 221: 55.37		RBP2_HUMAN (573-1152): 6.9e-53: 207: 19.12
+	Hs
		380528 K2C6B_HUMAN (4-407): 8.91e-87: 282: 21.85		ZRAN1_HUMAN (589-796): 5.46e-22: 105: 16.89
+	Hs
		360329 LMNA_HUMAN (3-550): 3.87e-63: 221: 55.37		RGPD5_HUMAN (1136-1440): 7.32e-39: 161: 16.72
+	Hs
		360224 LMNA_HUMAN (3-550): 3.87e-63: 221: 55.37		TITIN_HUMAN (92-940): 3.34e-30: 133: 9.98
+	Hs
		359712 LMNA_HUMAN (3-550): 3.87e-63: 221: 55.37		NU214_HUMAN (146-1306): 4.07e-29: 129: 11.13
+	Hs
		595459 LMNB1_HUMAN (1-586): 2.13e-71: 242: 100.00		ZRAN1_HUMAN (589-796): 5.46e-22: 105: 16.89
+	Hs
		595357 LMNB1_HUMAN (1-586): 2.13e-71: 242: 100.00		P121A_HUMAN (102-1074): 5.78e-16: 86: 9.24
+	Hs
		360512 LMNA_HUMAN (3-550): 3.87e-63: 221: 55.37		ZRAN1_HUMAN (589-796): 5.46e-22: 105: 16.89
+	Hs
		595471 LMNB1_HUMAN (1-586): 2.13e-71: 242: 100.00		SRRM2_HUMAN (145-1251): 4.61e-12: 73.7: 9.24
+	Ce
		106859 IFA4_CAEEL (3-549): 1.21e-72: 245: 26.64		NUP98_CAEEL (864-1253): 1.16e-10: 68.7: 14.57
+	Hs
		595161 LMNB1_HUMAN (1-586): 2.13e-71: 242: 100.00		NUP98_HUMAN (749-1368): 8.75e-11: 69.1: 12.83
+	Hs
		360279 LMNA_HUMAN (3-550): 3.87e-63: 221: 55.37		P121A_HUMAN (102-1074): 5.78e-16: 86: 9.24
+	Hs
		359790 LMNA_HUMAN (3-550): 3.87e-63: 221: 55.37		NUP98_HUMAN (749-1368): 8.75e-11: 69.1: 12.83