HitPredict

Interactor 1: LMNB1 (P20700)
Lamin-B1
Gene: LMNB1

Interactor 2: IMA1 (P52292)
Importin subunit alpha-1 (Karyopherin subunit alpha-2) (RAG cohort protein 1) (SRP1-alpha)
Gene: KPNA2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0016020 - membrane GO:0031965 - nuclear membrane
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 586 Hs			1 529
+	Hs
		359783 LMNA_HUMAN (3-550): 3.87e-63: 221: 55.37		IMA1_HUMAN (1-529): 6.78e-164: 477: 100.00
+	Hs
		134820 LMNA_HUMAN (3-550): 3.87e-63: 221: 55.37		IMA3_HUMAN (4-529): 5.61e-152: 446: 50.38
+	Hs
		238630 LMNB1_HUMAN (1-586): 2.13e-71: 242: 100.00		IMA7_HUMAN (1-528): 1.97e-141: 420: 45.37
+	Hs
		131360 LMNA_HUMAN (3-550): 3.87e-63: 221: 55.37		IMA4_HUMAN (4-529): 6.93e-148: 436: 49.06
+	Hs
		168617 LMNB1_HUMAN (1-586): 2.13e-71: 242: 100.00		IMA6_HUMAN (1-528): 9.99e-138: 410: 45.02
+	Dr
		71547 B3DKC5_DANRE (6-573): 3.64e-58: 207: 50.76		Q7ZVY9_DANRE (4-529): 5.3e-150: 441: 50.10
+	Hs
		238622 LMNA_HUMAN (3-550): 3.87e-63: 221: 55.37		IMA7_HUMAN (1-528): 1.97e-141: 420: 45.37
+	Hs
		595159 LMNB1_HUMAN (1-586): 2.13e-71: 242: 100.00		IMA5_HUMAN (4-528): 7.39e-133: 398: 44.47
+	Hs
		168609 LMNA_HUMAN (3-550): 3.87e-63: 221: 55.37		IMA6_HUMAN (1-528): 9.99e-138: 410: 45.02
+	Hs
		359784 LMNA_HUMAN (3-550): 3.87e-63: 221: 55.37		IMA5_HUMAN (4-528): 7.39e-133: 398: 44.47
+	Ce
		1091055 LMN1_CAEEL (28-549): 1.7e-58: 206: 32.01		IMA3_CAEEL (9-529): 1.3e-130: 391: 44.25
+	Dm
		445897 LAM0_DROME (12-586): 1.5e-52: 191: 34.92		IMA_DROME (6-529): 2.4e-121: 368: 48.30