HitPredict

Interactor 1: LMNB1 (P20700)
Lamin-B1
Gene: LMNB1

Interactor 2: RAC1 (P63000)
Ras-related C3 botulinum toxin substrate 1 (EC 3.6.5.2) (Cell migration-inducing gene 5 protein) (Ras-like protein TC25) (p21-Rac1)
Gene: RAC1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	19961560, 31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0016020 - membrane
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 586 Hs			1 192
+	Hs
		545206 LMNB1_HUMAN (1-586): 2.13e-71: 242: 100.00		RAC2_HUMAN (1-192): 1.2e-82: 244: 92.19
+	Hs
		595170 LMNB1_HUMAN (1-586): 2.13e-71: 242: 100.00		RAC3_HUMAN (1-191): 2.72e-79: 236: 93.19
+	Hs
		595192 LMNB1_HUMAN (1-586): 2.13e-71: 242: 100.00		RHOG_HUMAN (1-192): 3.1e-79: 236: 71.35
+	Hs
		595171 LMNB1_HUMAN (1-586): 2.13e-71: 242: 100.00		CDC42_HUMAN (1-192): 1.4e-78: 234: 70.31
+	Hs
		595175 LMNB1_HUMAN (1-586): 2.13e-71: 242: 100.00		RHOA_HUMAN (5-192): 3.5e-77: 230: 57.98
+	Hs
		925217 LMNB2_HUMAN (20-586): 5.03e-61: 215: 56.22		RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00
+	Hs
		436157 LMNB1_HUMAN (1-586): 2.13e-71: 242: 100.00		RHOC_HUMAN (5-192): 8.68e-75: 224: 57.45
+	Hs
		545336 LMNB2_HUMAN (20-586): 5.03e-61: 215: 56.22		RAC2_HUMAN (1-192): 1.2e-82: 244: 92.19
+	Hs
		975734 LMNB2_HUMAN (20-586): 5.03e-61: 215: 56.22		RHOJ_HUMAN (2-189): 1.38e-80: 240: 60.64
+	Hs
		892329 LMNB2_HUMAN (20-586): 5.03e-61: 215: 56.22		RAC3_HUMAN (1-191): 2.72e-79: 236: 93.19
+	Hs
		950939 LMNB2_HUMAN (20-586): 5.03e-61: 215: 56.22		RHOG_HUMAN (1-192): 3.1e-79: 236: 71.35
+	Hs
		893923 LMNB2_HUMAN (20-586): 5.03e-61: 215: 56.22		CDC42_HUMAN (1-192): 1.4e-78: 234: 70.31
+	Hs
		359580 LMNA_HUMAN (3-550): 3.87e-63: 221: 55.37		RHOC_HUMAN (5-192): 8.68e-75: 224: 57.45
+	Hs
		900400 LMNB2_HUMAN (20-586): 5.03e-61: 215: 56.22		RHOA_HUMAN (5-192): 3.5e-77: 230: 57.98
+	Hs
		436265 LMNB2_HUMAN (20-586): 5.03e-61: 215: 56.22		RHOC_HUMAN (5-192): 8.68e-75: 224: 57.45