HitPredict

Interactor 1: LMNB1 (P20700)
Lamin-B1
Gene: LMNB1

Interactor 2: PRP8 (Q6P2Q9)
Pre-mRNA-processing-splicing factor 8 (220 kDa U5 snRNP-specific protein) (PRP8 homolog) (Splicing factor Prp8) (p220)
Gene: PRPF8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0016020 - membrane
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 586 Hs			1 2335
+	Hs
		359504 K2C6A_HUMAN (4-407): 1.22e-124: 380: 22.82		PRP8_HUMAN (1-2335): 0: 4632: 100.00
+	Hs
		531588 K2C5_HUMAN (4-391): 3.18e-123: 377: 23.74		PRP8_HUMAN (1-2335): 0: 4632: 100.00
+	Hs
		380490 K2C6B_HUMAN (4-407): 8.91e-87: 282: 21.85		PRP8_HUMAN (1-2335): 0: 4632: 100.00
+	Hs
		360051 LMNA_HUMAN (3-550): 3.87e-63: 221: 55.37		PRP8_HUMAN (1-2335): 0: 4632: 100.00
+	Hs
		318826 K2C75_HUMAN (4-391): 1.8e-50: 184: 20.61		PRP8_HUMAN (1-2335): 0: 4632: 100.00
+	Hs
		943681 KRT85_HUMAN (54-390): 2.42e-49: 180: 20.35		PRP8_HUMAN (1-2335): 0: 4632: 100.00
+	Hs
		443593 VIME_HUMAN (28-390): 5.22e-30: 125: 28.65		PRP8_HUMAN (1-2335): 0: 4632: 100.00