HitPredict

Interactor 1: GRAH (P20718)
Granzyme H (EC 3.4.21.-) (CCP-X) (Cathepsin G-like 2) (CTSGL2) (Cytotoxic T-lymphocyte proteinase) (Cytotoxic serine protease C) (CSP-C)
Gene: GZMH

Interactor 2: TBB8 (Q3ZCM7)
Tubulin beta-8 chain (Tubulin beta 8 class VIII)
Gene: TUBB8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 246 Hs			1 444
+	Hs
		428722 TRY2_HUMAN (1-244): 5.94e-106: 308: 31.87		TBB3_HUMAN (1-442): 0: 719: 86.43
+	Hs
		428017 GRAH_HUMAN (1-246): 4.91e-102: 298: 100.00		TBB5_HUMAN (1-429): 0: 720: 89.74
+	Hs
		595528 GRAH_HUMAN (1-246): 4.91e-102: 298: 100.00		TBB3_HUMAN (1-442): 0: 719: 86.43
+	Hs
		427973 CATG_HUMAN (1-246): 7.55e-101: 295: 57.32		TBB5_HUMAN (1-429): 0: 720: 89.74
+	Hs
		381123 GRAH_HUMAN (1-246): 4.91e-102: 298: 100.00		TBB4A_HUMAN (1-427): 0: 715: 90.16
+	Hs
		1037334 KLK6_HUMAN (1-244): 1.1e-99: 292: 30.65		TBB3_HUMAN (1-442): 0: 719: 86.43
+	Hs
		439334 CATG_HUMAN (1-246): 7.55e-101: 295: 57.32		TBB8_HUMAN (1-427): 0: 708: 100.00
+	Hs
		1037427 KLK11_HUMAN (15-244): 5.26e-94: 278: 36.40		TBB3_HUMAN (1-442): 0: 719: 86.43
+	Hs
		381216 PRSS8_HUMAN (13-246): 8.72e-94: 280: 29.80		TBB4A_HUMAN (1-427): 0: 715: 90.16
+	Hs
		428014 TRYB2_HUMAN (14-240): 2.8e-91: 271: 29.76		TBB5_HUMAN (1-429): 0: 720: 89.74
+	Hs
		589991 TRYB2_HUMAN (14-240): 2.8e-91: 271: 29.76		TBB4B_HUMAN (1-427): 0: 719: 91.10
+	Hs
		589992 TRYB2_HUMAN (14-240): 2.8e-91: 271: 29.76		TBB3_HUMAN (1-442): 0: 719: 86.43
+	Hs
		589997 TRYB2_HUMAN (14-240): 2.8e-91: 271: 29.76		TBB2B_HUMAN (1-430): 0: 719: 90.23
+	Hs
		381121 TRYB2_HUMAN (14-240): 2.8e-91: 271: 29.76		TBB4A_HUMAN (1-427): 0: 715: 90.16
+	Hs
		589993 TRYB2_HUMAN (14-240): 2.8e-91: 271: 29.76		TBB2A_HUMAN (1-430): 0: 715: 90.00
+	Hs
		1114231 KLK15_HUMAN (11-245): 1.85e-92: 274: 36.40		TBB8_HUMAN (1-427): 0: 708: 100.00
+	Hs
		621370 CMA1_HUMAN (13-244): 2.01e-92: 273: 47.86		TBB8_HUMAN (1-427): 0: 708: 100.00
+	Hs
		589994 TRYB2_HUMAN (14-240): 2.8e-91: 271: 29.76		TBB8_HUMAN (1-427): 0: 708: 100.00
+	Hs
		420746 KLK1_HUMAN (1-245): 4.51e-91: 270: 31.96		TBB8_HUMAN (1-427): 0: 708: 100.00
+	Hs
		836354 GRAK_HUMAN (4-243): 1.9e-45: 154: 37.95		TBB3_HUMAN (1-442): 0: 719: 86.43