HitPredict

Interactor 1: GRAH (P20718)
Granzyme H (EC 3.4.21.-) (CCP-X) (Cathepsin G-like 2) (CTSGL2) (Cytotoxic T-lymphocyte proteinase) (Cytotoxic serine protease C) (CSP-C)
Gene: GZMH

Interactor 2: TBA1C (Q9BQE3)
Tubulin alpha-1C chain (EC 3.6.5.-) (Alpha-tubulin 6) (Tubulin alpha-6 chain) [Cleaved into: Detyrosinated tubulin alpha-1C chain]
Gene: TUBA1C

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 246 Hs			1 449
+	Hs
		714751 TRY3_HUMAN (8-244): 2.54e-106: 311: 31.95		TBA1B_HUMAN (1-439): 0: 717: 99.09
+	Hs
		595527 GRAH_HUMAN (1-246): 4.91e-102: 298: 100.00		TBA4A_HUMAN (1-448): 0: 724: 96.21
+	Hs
		933554 KLK6_HUMAN (1-244): 1.1e-99: 292: 30.65		TBA4A_HUMAN (1-448): 0: 724: 96.21
+	Hs
		595544 GRAH_HUMAN (1-246): 4.91e-102: 298: 100.00		TBA1A_HUMAN (1-439): 0: 715: 99.09
+	Hs
		1309527 KLK11_HUMAN (15-244): 5.26e-94: 278: 36.40		TBA1C_HUMAN (1-449): 0: 733: 100.00
+	Hs
		439340 CATG_HUMAN (1-246): 7.55e-101: 295: 57.32		TBA1A_HUMAN (1-439): 0: 715: 99.09
+	Hs
		1309491 KLK15_HUMAN (11-245): 1.85e-92: 274: 36.40		TBA1C_HUMAN (1-449): 0: 733: 100.00
+	Hs
		486167 GRAB_HUMAN (1-245): 5.54e-100: 292: 71.55		TBA1A_HUMAN (1-439): 0: 715: 99.09
+	Hs
		589996 TRYB2_HUMAN (14-240): 2.8e-91: 271: 29.76		TBA1C_HUMAN (1-449): 0: 733: 100.00
+	Hs
		933653 KLK11_HUMAN (15-244): 5.26e-94: 278: 36.40		TBA4A_HUMAN (1-448): 0: 724: 96.21
+	Hs
		933613 KLK15_HUMAN (11-245): 1.85e-92: 274: 36.40		TBA4A_HUMAN (1-448): 0: 724: 96.21
+	Hs
		428017 GRAH_HUMAN (1-246): 4.91e-102: 298: 100.00		TBB5_HUMAN (1-439): 0: 699: 41.00
+	Hs
		933221 PRSS8_HUMAN (13-246): 8.72e-94: 280: 29.80		TBA1B_HUMAN (1-439): 0: 717: 99.09
+	Hs
		427973 CATG_HUMAN (1-246): 7.55e-101: 295: 57.32		TBB5_HUMAN (1-439): 0: 699: 41.00
+	Hs
		1175223 KLK11_HUMAN (15-244): 5.26e-94: 278: 36.40		TBA1A_HUMAN (1-439): 0: 715: 99.09
+	Hs
		1175174 KLK15_HUMAN (11-245): 1.85e-92: 274: 36.40		TBA1A_HUMAN (1-439): 0: 715: 99.09
+	Hs
		589995 TRYB2_HUMAN (14-240): 2.8e-91: 271: 29.76		TBA1A_HUMAN (1-439): 0: 715: 99.09
+	Hs
		428014 TRYB2_HUMAN (14-240): 2.8e-91: 271: 29.76		TBB5_HUMAN (1-439): 0: 699: 41.00
+	Hs
		589991 TRYB2_HUMAN (14-240): 2.8e-91: 271: 29.76		TBB4B_HUMAN (1-437): 0: 697: 40.73
+	Hs
		589997 TRYB2_HUMAN (14-240): 2.8e-91: 271: 29.76		TBB2B_HUMAN (1-440): 0: 697: 40.23