HitPredict

Interactor 1: BMP6 (P20722)
Bone morphogenetic protein 6 (BMP-6) (VG-1-related protein) (VGR-1)
Gene: BMP6

Interactor 2: CRDL2 (Q8VEA6)
Chordin-like protein 2
Gene: Chrdl2

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	14660436
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001503 - ossification GO:0005615 - extracellular space
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 510 Mm			1 426
+	Mm
		823193 BMP5_MOUSE (61-510): 7.66e-162: 468: 59.33		CRDL2_MOUSE (1-426): 2.8e-92: 286: 100.00
+	Mm
		615510 BMP7_MOUSE (32-510): 1.89e-159: 461: 54.43		CRDL2_MOUSE (1-426): 2.8e-92: 286: 100.00
+	Mm
		597616 BMP2_MOUSE (86-509): 3.71e-107: 326: 28.05		CRDL2_MOUSE (1-426): 2.8e-92: 286: 100.00
+	Mm
		597618 BMP4_MOUSE (86-509): 1.89e-104: 320: 27.59		CRDL2_MOUSE (1-426): 2.8e-92: 286: 100.00
+	Mm
		792933 GDF5_MOUSE (26-509): 2.68e-102: 317: 21.34		CRDL2_MOUSE (1-426): 2.8e-92: 286: 100.00
+	Hs
		439888 INHBA_HUMAN (102-509): 2.9e-93: 292: 19.68		CRDL2_HUMAN (1-425): 3.17e-80: 255: 72.49
+	Dm
		646121 60A_DROME (31-510): 1.27e-128: 384: 31.20		Q9W2H2_DROME (138-315): 7.73e-11: 66.1: 17.58
+	Hs
		351256 TGFB1_HUMAN (162-509): 8.57e-68: 224: 21.82		TENX_HUMAN (1-357): 4e-50: 184: 13.24
+	Rn
		566271 TGFB1_RAT (162-509): 1.66e-75: 244: 22.38		Q71SA3_RAT (28-338): 1.56e-42: 162: 16.62
+	Hs
		358592 BMP2_HUMAN (86-509): 1.03e-105: 323: 28.83		CO2A1_HUMAN (214-321): 1.93e-15: 80.7: 23.15
+	Xl
		1265027 Q91597_XENLA (125-510): 4.48e-93: 290: 27.41		CHRD_XENLA (21-196): 8.41e-21: 97.3: 26.88
+	Mm
		597617 BMP4_MOUSE (86-509): 1.89e-104: 320: 27.59		BMPER_MOUSE (22-235): 2.18e-10: 64.6: 18.47
+	Hs
		351223 TGFB1_HUMAN (162-509): 8.57e-68: 224: 21.82		TSP1_HUMAN (28-338): 4.15e-41: 158: 16.92
+	Dm
		871198 SCW_DROME (95-510): 8.12e-98: 303: 25.00		SOG_DROME (191-347): 1.33e-10: 65.7: 18.44
+	Dm
		429979 DECA_DROME (94-509): 6.78e-89: 285: 25.79		Q9W2H2_DROME (138-315): 7.73e-11: 66.1: 17.58
+	Dm
		429968 DECA_DROME (94-509): 6.78e-89: 285: 25.79		SOG_DROME (191-347): 1.33e-10: 65.7: 18.44
+	Hs
		155756 GDF8_HUMAN (139-509): 7.53e-78: 250: 22.85		LAMB2_HUMAN (79-317): 3.9e-09: 61.1: 10.90
+	Hs
		351208 TGFB1_HUMAN (162-509): 8.57e-68: 224: 21.82		CO2A1_HUMAN (214-321): 1.93e-15: 80.7: 23.15
+	Mm
		380162 TGFB1_MOUSE (162-509): 1.59e-74: 242: 22.10		CO1A1_MOUSE (106-187): 8.32e-09: 59.9: 22.89
+	Hs
		351222 TGFB1_HUMAN (162-509): 8.57e-68: 224: 21.82		LAMB1_HUMAN (32-255): 2.04e-10: 64.9: 12.30