Interactor 1: IL11 (P20809)
Interleukin-11 (IL-11) (Adipogenesis inhibitory factor) (AGIF) (Oprelvekin)
Gene: IL11

Interactor 2: I11RA (Q14626)
Interleukin-11 receptor subunit alpha (IL-11 receptor subunit alpha) (IL-11R subunit alpha) (IL-11R-alpha) (IL-11RA) [Cleaved into: Soluble interleukin-11 receptor subunit alpha (sIL-11R) (sIL-11RA) (sIL11RA)]
Gene: IL11RA

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.62 0.60 0.611

The method score is based on:

Property Details
Experiments 8940087, 26551460
Identification Methods coimmunoprecipitation, anti tag coimmunoprecipitation, surface plasmon resonance
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005576 - extracellular region
GO:0008284 - positive regulation of cell population proliferation
GO:0038154 - interleukin-11-mediated signaling pathway
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 199
Hs

1 422
+ Mm
+ Hs
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024