Interactor 1: CP3A5 (P20815)
Cytochrome P450 3A5 (EC 1.14.14.1) (CYPIIIA5) (Cytochrome P450-PCN3)
Gene: CYP3A5

Interactor 2: CP3A7 (P24462)
Cytochrome P450 3A7 (EC 1.14.14.1) (CYPIIIA7) (Cytochrome P450-HFLA) (P450HLp2)
Gene: CYP3A7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.65 1.00 0.811

The method score is based on:

Property Details
Experiments 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains p450~p450
Common GO terms GO:0002933 - lipid hydroxylation
GO:0004497 - monooxygenase activity
GO:0005506 - iron ion binding
GO:0005789 - endoplasmic reticulum membrane
GO:0006805 - xenobiotic metabolic process
and 11 others

more...

Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 502
Hs

1 503
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Oc
+ Hs
+ Hs
+ Dm
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024