HitPredict

Interactor 1: FILA (P20930)
Filaggrin
Gene: FLG

Interactor 2: VHL (P40337)
von Hippel-Lindau disease tumor suppressor (Protein G7) (pVHL)
Gene: VHL

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	17353931
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 4061 Hs			1 213
+	Hs
		441058 CO4A2_HUMAN (3241-4046): 4.47e-44: 180: 8.51		VHL_HUMAN (1-213): 3.45e-146: 407: 100.00
+	Hs
		771960 CO4A6_HUMAN (3298-4050): 4.18e-40: 167: 8.48		VHL_HUMAN (1-213): 3.45e-146: 407: 100.00
+	Hs
		685162 S10AB_HUMAN (2-102): 4.49e-42: 152: 30.69		VHL_HUMAN (1-213): 3.45e-146: 407: 100.00
+	Hs
		416376 S10A9_HUMAN (1-102): 2.02e-40: 148: 35.92		VHL_HUMAN (1-213): 3.45e-146: 407: 100.00
+	Hs
		771920 CO4A3_HUMAN (3269-4046): 2.64e-32: 141: 8.47		VHL_HUMAN (1-213): 3.45e-146: 407: 100.00
+	Hs
		396702 S10A8_HUMAN (1-95): 1.16e-36: 136: 27.37		VHL_HUMAN (1-213): 3.45e-146: 407: 100.00
+	Hs
		358658 CO4A1_HUMAN (3387-4043): 1.02e-29: 133: 7.64		VHL_HUMAN (1-213): 3.45e-146: 407: 100.00