HitPredict

Interactor 1: RASA1 (P20936)
Ras GTPase-activating protein 1 (GAP) (GTPase-activating protein) (RasGAP) (Ras p21 protein activator) (p120GAP)
Gene: RASA1

Interactor 2: CDN2A (P42771)
Cyclin-dependent kinase inhibitor 2A (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (Multiple tumor suppressor 1) (MTS-1) (p16-INK4a) (p16-INK4) (p16INK4A)
Gene: CDKN2A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	24412244
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001953 - negative regulation of cell-matrix adhesion GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 1047 Hs			1 156
+	Mm
		100050 SYGP1_MOUSE (375-1030): 3.98e-106: 363: 19.45		ANK2_MOUSE (3-155): 1.8e-37: 137: 17.37
+	Hs
		965139 SYGP1_HUMAN (375-1030): 6.69e-106: 362: 19.45		ANK2_HUMAN (3-155): 1.76e-37: 137: 17.37
+	Hs
		790705 IQGA1_HUMAN (394-1044): 2.98e-94: 331: 12.78		CDN2A_HUMAN (1-156): 1.38e-51: 163: 100.00
+	Hs
		556720 SYGP1_HUMAN (375-1030): 6.69e-106: 362: 19.45		ANK1_HUMAN (2-130): 2.4e-33: 125: 24.62
+	Hs
		60399 SYGP1_HUMAN (375-1030): 6.69e-106: 362: 19.45		POTEF_HUMAN (1-130): 1.26e-29: 115: 19.55
+	Hs
		1164363 SYGP1_HUMAN (375-1030): 6.69e-106: 362: 19.45		POTEE_HUMAN (49-152): 2.11e-18: 82.7: 14.82
+	Hs
		1021395 IQGA2_HUMAN (460-1044): 2.27e-84: 301: 13.18		ANK3_HUMAN (15-155): 1.26e-35: 132: 21.13
+	Hs
		1299786 SYGP1_HUMAN (375-1030): 6.69e-106: 362: 19.45		KDIS_HUMAN (86-156): 1.81e-12: 65.8: 19.48
+	Hs
		1299772 SYGP1_HUMAN (375-1030): 6.69e-106: 362: 19.45		RAI14_HUMAN (1-64): 1.97e-11: 62.7: 21.21
+	Mm
		56839 SYGP1_MOUSE (375-1030): 3.98e-106: 363: 19.45		TANC2_MOUSE (1-99): 3.54e-10: 59.3: 21.57
+	Hs
		1299752 SYGP1_HUMAN (375-1030): 6.69e-106: 362: 19.45		TANC2_HUMAN (1-99): 3.54e-10: 59.3: 21.57
+	Hs
		883552 IQGA3_HUMAN (401-1044): 1.11e-77: 281: 12.22		RIPK4_HUMAN (9-155): 1.21e-30: 117: 25.68
+	Hs
		1201452 IQGA3_HUMAN (401-1044): 1.11e-77: 281: 12.22		Q9H4D1_HUMAN (9-155): 2.04e-30: 116: 25.68
+	Hs
		809460 IQGA1_HUMAN (394-1044): 2.98e-94: 331: 12.78		RAI14_HUMAN (1-64): 1.97e-11: 62.7: 21.21
+	Hs
		598527 NF1_HUMAN (720-1040): 4.33e-81: 293: 24.44		TANC2_HUMAN (1-99): 3.54e-10: 59.3: 21.57
+	Hs
		924484 GRB2_HUMAN (181-317): 1.08e-10: 64.3: 30.71		ANK2_HUMAN (3-155): 1.76e-37: 137: 17.37
+	Hs
		924794 GRB2_HUMAN (181-317): 1.08e-10: 64.3: 30.71		EHMT2_HUMAN (4-114): 3.84e-29: 113: 24.11
+	Hs
		924913 GRB2_HUMAN (181-317): 1.08e-10: 64.3: 30.71		RAI14_HUMAN (1-64): 1.97e-11: 62.7: 21.21