HitPredict - High confidence protein-protein interactions

Interactor 1: CD3Z (P20963)
T-cell surface glycoprotein CD3 zeta chain (T-cell receptor T3 zeta chain) (CD antigen CD247)
Gene: CD247

Interactor 2: CD3Z (P20963)
T-cell surface glycoprotein CD3 zeta chain (T-cell receptor T3 zeta chain) (CD antigen CD247)
Gene: CD247

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.67	1.00	0.820

Property	Details
Experiments	17055436, 24502978
Identification Methods	nuclear magnetic resonance, comigration in non denaturing gel electrophoresis, comigration in gel electrophoresis, anti bait coimmunoprecipitation, pull down
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	TCR_zetazeta~TCR_zetazeta
Common GO terms	GO:0002250 - adaptive immune response GO:0004888 - transmembrane signaling receptor activity GO:0005737 - cytoplasm GO:0005794 - Golgi apparatus GO:0005886 - plasma membrane and 15 others more... GO:0007166 - cell surface receptor signaling pathway GO:0033001 - Fc-gamma receptor III complex GO:0038094 - Fc-gamma receptor signaling pathway GO:0042101 - T cell receptor complex GO:0042105 - alpha-beta T cell receptor complex GO:0042106 - gamma-delta T cell receptor complex GO:0042803 - protein homodimerization activity GO:0046629 - gamma-delta T cell activation GO:0046631 - alpha-beta T cell activation GO:0046982 - protein heterodimerization activity GO:0050852 - T cell receptor signaling pathway GO:0051259 - protein complex oligomerization GO:0065003 - protein-containing complex assembly GO:1990782 - protein tyrosine kinase binding GO:2000010 - positive regulation of protein localization to cell surface
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1	164
Hs

1	164

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024