Interactor 1: CD3Z (P20963)
T-cell surface glycoprotein CD3 zeta chain (T-cell receptor T3 zeta chain) (CD antigen CD247)
Gene: CD247

Interactor 2: CSK (P41240)
Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-Src kinase) (Protein-tyrosine kinase CYL)
Gene: CSK

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.52 0.60 0.561

The method score is based on:

Property Details
Experiments 8621646
Identification Methods pull down, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0002250 - adaptive immune response
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0050852 - T cell receptor signaling pathway
GO:1990782 - protein tyrosine kinase binding
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 164
Hs

1 450
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024