HitPredict

Interactor 1: CD11B (P21127)
Cyclin-dependent kinase 11B (EC 2.7.11.22) (Cell division cycle 2-like protein kinase 1) (CLK-1) (Cell division protein kinase 11B) (Galactosyltransferase-associated protein kinase p58/GTA) (PITSLRE serine/threonine-protein kinase CDC2L1) (p58 CLK-1)
Gene: CDK11B

Interactor 2: H11 (Q02539)
Histone H1.1 (Histone H1a)
Gene: H1-1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	21078675
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 795 Hs			1 215
+	Hs
		488902 CD11B_HUMAN (1-795): 0: 574: 100.00		H14_HUMAN (1-149): 9.6e-22: 90.5: 63.76
+	Rn
		413197 Q6P751_RAT (435-731): 2.12e-154: 453: 44.30		H1T_RAT (1-213): 4.75e-37: 130: 48.37
+	Hs
		559328 CDK2_HUMAN (435-731): 1.45e-154: 454: 43.96		H13_HUMAN (1-169): 5.79e-27: 104: 55.03
+	Rn
		88903 Q6P751_RAT (435-731): 2.12e-154: 453: 44.30		H11_RAT (1-123): 9.41e-24: 95.9: 77.24
+	Hs
		558990 CDK2_HUMAN (435-731): 1.45e-154: 454: 43.96		H15_HUMAN (1-118): 1.18e-22: 93.2: 72.88
+	Hs
		625377 CDK2_HUMAN (435-731): 1.45e-154: 454: 43.96		H11_HUMAN (1-199): 7.29e-21: 88.2: 100.00
+	Mm
		794656 CDK2_MOUSE (435-731): 8.4e-145: 431: 38.15		H15_MOUSE (1-199): 6.17e-23: 94: 56.59
+	Hs
		414717 CDK1_HUMAN (435-726): 7.24e-138: 411: 41.84		H13_HUMAN (1-169): 5.79e-27: 104: 55.03
+	Mm
		550489 CDK2_MOUSE (435-731): 8.4e-145: 431: 38.15		H12_MOUSE (33-118): 1.42e-17: 79.4: 80.23
+	Mm
		794643 CDK2_MOUSE (435-731): 8.4e-145: 431: 38.15		H11_MOUSE (1-124): 1.61e-17: 79.4: 79.84
+	Rn
		88899 CDK1_RAT (435-726): 2.11e-137: 410: 42.18		H11_RAT (1-123): 9.41e-24: 95.9: 77.24
+	Hs
		414716 CDK1_HUMAN (435-726): 7.24e-138: 411: 41.84		H15_HUMAN (1-118): 1.18e-22: 93.2: 72.88
+	Hs
		559654 CDK5_HUMAN (435-729): 1.29e-137: 410: 41.55		H12_HUMAN (32-175): 4.83e-23: 94: 54.86
+	Hs
		559065 CDK5_HUMAN (435-729): 1.29e-137: 410: 41.55		H15_HUMAN (1-118): 1.18e-22: 93.2: 72.88
+	Hs
		489003 CDK5_HUMAN (435-729): 1.29e-137: 410: 41.55		H14_HUMAN (1-149): 9.6e-22: 90.5: 63.76
+	Hs
		414874 CDK1_HUMAN (435-726): 7.24e-138: 411: 41.84		H11_HUMAN (1-199): 7.29e-21: 88.2: 100.00
+	Hs
		960270 CDK5_HUMAN (435-729): 1.29e-137: 410: 41.55		H11_HUMAN (1-199): 7.29e-21: 88.2: 100.00
+	Mm
		794639 CDK5_MOUSE (435-729): 1.94e-137: 410: 41.55		H11_MOUSE (1-124): 1.61e-17: 79.4: 79.84
+	Mm
		509461 CDK1_MOUSE (435-726): 4.35e-136: 406: 42.18		H12_MOUSE (33-118): 1.42e-17: 79.4: 80.23
+	Mm
		509472 CDK1_MOUSE (435-726): 4.35e-136: 406: 42.18		H11_MOUSE (1-124): 1.61e-17: 79.4: 79.84