HitPredict

Interactor 1: CD11B (P21127)
Cyclin-dependent kinase 11B (EC 2.7.11.22) (Cell division cycle 2-like protein kinase 1) (CLK-1) (Cell division protein kinase 11B) (Galactosyltransferase-associated protein kinase p58/GTA) (PITSLRE serine/threonine-protein kinase CDC2L1) (p58 CLK-1)
Gene: CDK11B

Interactor 2: FKBP5 (Q13451)
Peptidyl-prolyl cis-trans isomerase FKBP5 (PPIase FKBP5) (EC 5.2.1.8) (51 kDa FK506-binding protein) (51 kDa FKBP) (FKBP-51) (54 kDa progesterone receptor-associated immunophilin) (Androgen-regulated protein 6) (FF1 antigen) (FK506-binding protein 5) (FKBP-5) (FKBP54) (p54) (HSP90-binding immunophilin) (Rotamase)
Gene: FKBP5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.789

Property	Details
Experiments	33961781, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	FKBP_C~Pkinase
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 795 Hs			1 457
+	Hs
		1035053 CD11A_HUMAN (1-795): 0: 561: 96.86		FKBP5_HUMAN (1-457): 6.63e-145: 423: 100.00
+	Hs
		960090 CDK3_HUMAN (435-731): 8.54e-148: 436: 45.64		FKBP5_HUMAN (1-457): 6.63e-145: 423: 100.00
+	Hs
		625378 CDK2_HUMAN (435-731): 1.45e-154: 454: 43.96		FKBP4_HUMAN (1-456): 1.79e-136: 402: 54.59
+	Hs
		414904 CDK1_HUMAN (435-726): 7.24e-138: 411: 41.84		FKBP5_HUMAN (1-457): 6.63e-145: 423: 100.00
+	Hs
		960281 CDK5_HUMAN (435-729): 1.29e-137: 410: 41.55		FKBP5_HUMAN (1-457): 6.63e-145: 423: 100.00
+	Hs
		1034862 CDK10_HUMAN (429-760): 3.17e-133: 401: 52.41		FKBP5_HUMAN (1-457): 6.63e-145: 423: 100.00
+	Hs
		960271 CDK5_HUMAN (435-729): 1.29e-137: 410: 41.55		FKBP4_HUMAN (1-456): 1.79e-136: 402: 54.59
+	Hs
		841189 CDK7_HUMAN (436-760): 1.13e-72: 243: 38.69		FKBP5_HUMAN (1-457): 6.63e-145: 423: 100.00
+	Hs
		684635 CDK3_HUMAN (435-731): 8.54e-148: 436: 45.64		STIP1_HUMAN (265-457): 3.91e-23: 104: 17.62
+	Hs
		414775 CDK1_HUMAN (435-726): 7.24e-138: 411: 41.84		STIP1_HUMAN (265-457): 3.91e-23: 104: 17.62
+	Hs
		684636 CDK5_HUMAN (435-729): 1.29e-137: 410: 41.55		STIP1_HUMAN (265-457): 3.91e-23: 104: 17.62
+	Hs
		684741 CDK10_HUMAN (429-760): 3.17e-133: 401: 52.41		STIP1_HUMAN (265-457): 3.91e-23: 104: 17.62