HitPredict

Interactor 1: PABP (P21187)
Polyadenylate-binding protein (PABP) (Poly(A)-binding protein)
Gene: PABP

Interactor 2: LARP (Q9VAW5)
La-related protein 1 (dLarp)
Gene: LARP

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	19631203
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	La~RRM_1
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0007140 - male meiotic nuclear division GO:0010494 - cytoplasmic stress granule GO:0045727 - positive regulation of translation
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 634 Dm			1 1673
+	Hs
		516616 PABP1_HUMAN (1-633): 3.27e-169: 498: 57.19		LAR4B_HUMAN (565-1284): 6.38e-81: 285: 13.91
+	Hs
		516595 PABP1_HUMAN (1-633): 3.27e-169: 498: 57.19		KMT2C_HUMAN (41-1281): 1.27e-56: 220: 10.92
+	Hs
		516568 PABP1_HUMAN (1-633): 3.27e-169: 498: 57.19		LARP4_HUMAN (621-1284): 3.91e-46: 181: 12.57
+	Hs
		516541 PABP1_HUMAN (1-633): 3.27e-169: 498: 57.19		LARP7_HUMAN (727-1221): 1e-29: 128: 12.09
+	Hs
		516561 PABP1_HUMAN (1-633): 3.27e-169: 498: 57.19		LARP1_HUMAN (322-1200): 1.96e-25: 116: 14.05
+	Hs
		1116304 PAP1L_HUMAN (1-633): 2.53e-154: 460: 50.87		LARP7_HUMAN (727-1221): 1e-29: 128: 12.09
+	Hs
		516553 PABP1_HUMAN (1-633): 3.27e-169: 498: 57.19		LAR1B_HUMAN (560-1158): 1.63e-13: 78.1: 12.56
+	At
		790116 PABP2_ARATH (2-629): 1.3e-142: 430: 41.40		LRP6C_ARATH (692-1067): 5.48e-35: 142: 15.98
+	At
		285476 PABP2_ARATH (2-629): 1.3e-142: 430: 41.40		LRP6B_ARATH (686-1068): 3.18e-34: 141: 15.06
+	Hs
		516609 PABP1_HUMAN (1-633): 3.27e-169: 498: 57.19		TITIN_HUMAN (8-853): 1.12e-09: 66.1: 9.20
+	Hs
		1268142 PABP5_HUMAN (94-388): 1.14e-57: 200: 28.72		LAR4B_HUMAN (565-1284): 6.38e-81: 285: 13.91
+	Hs
		1174835 PABP5_HUMAN (94-388): 1.14e-57: 200: 28.72		LARP4_HUMAN (621-1284): 3.91e-46: 181: 12.57
+	Hs
		1162644 PABP5_HUMAN (94-388): 1.14e-57: 200: 28.72		LARP1_HUMAN (322-1200): 1.96e-25: 116: 14.05
+	Hs
		403080 NUCL_HUMAN (90-375): 6.39e-39: 154: 20.62		LA_HUMAN (729-943): 1.61e-30: 128: 18.47
+	Hs
		582322 NUCL_HUMAN (90-375): 6.39e-39: 154: 20.62		LARP7_HUMAN (727-1221): 1e-29: 128: 12.09
+	Hs
		1145698 PABP5_HUMAN (94-388): 1.14e-57: 200: 28.72		LAR1B_HUMAN (560-1158): 1.63e-13: 78.1: 12.56
+	At
		285478 PABP8_ARATH (179-374): 8.86e-31: 129: 27.41		LRP6B_ARATH (686-1068): 3.18e-34: 141: 15.06
+	Hs
		1116542 PABP3_HUMAN (173-375): 1.03e-28: 123: 26.47		LARP7_HUMAN (727-1221): 1e-29: 128: 12.09
+	Hs
		582292 NUCL_HUMAN (90-375): 6.39e-39: 154: 20.62		MDC1_HUMAN (363-1332): 9.96e-17: 88.9: 8.40
+	Hs
		582409 NUCL_HUMAN (90-375): 6.39e-39: 154: 20.62		TITIN_HUMAN (8-853): 1.12e-09: 66.1: 9.20