HitPredict

Interactor 1: KLRG2 (A4D1S0)
Killer cell lectin-like receptor subfamily G member 2 (C-type lectin domain family 15 member B)
Gene: KLRG2

Interactor 2: EPHB4 (P54760)
Ephrin type-B receptor 4 (EC 2.7.10.1) (Hepatoma transmembrane kinase) (Tyrosine-protein kinase TYRO11)
Gene: EPHB4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.80	0.726

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	fn3~Lectin_C
Common GO terms	-
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 409 Hs			1 987
+	Hs
		59743 KLRG2_HUMAN (1-409): 9.69e-75: 240: 100.00		EPHB1_HUMAN (16-975): 0: 1118: 56.55
+	Hs
		59744 KLRG2_HUMAN (1-409): 9.69e-75: 240: 100.00		EPHA4_HUMAN (3-981): 0: 1093: 49.70
+	Hs
		644550 NKG2A_HUMAN (203-405): 1.39e-44: 156: 20.55		EPHB4_HUMAN (1-987): 0: 1122: 100.00
+	Hs
		872591 CLC4A_HUMAN (256-406): 8.15e-43: 151: 16.46		EPHB4_HUMAN (1-987): 0: 1122: 100.00
+	Hs
		872538 CL12B_HUMAN (245-408): 1.12e-41: 150: 21.39		EPHB4_HUMAN (1-987): 0: 1122: 100.00
+	Hs
		1072563 CLC4D_HUMAN (276-405): 1.16e-44: 155: 19.72		EPHA7_HUMAN (3-981): 0: 1100: 48.64
+	Hs
		600705 CLC4A_HUMAN (256-406): 8.15e-43: 151: 16.46		EPHA1_HUMAN (11-969): 0: 944: 40.17
+	Rn
		439304 ASGR2_RAT (125-408): 8.57e-69: 221: 15.46		INSR_RAT (380-879): 6.3e-136: 444: 30.43
+	Rn
		362129 ASGR1_RAT (225-405): 1.56e-52: 178: 16.75		INSR_RAT (380-879): 6.3e-136: 444: 30.43
+	Mm
		639453 CLC7A_MOUSE (281-407): 8.56e-26: 106: 21.99		LYN_MOUSE (599-875): 7.4e-62: 221: 41.37