HitPredict

Interactor 1: NEST (P21263)
Nestin
Gene: Nes

Interactor 2: CDK5 (Q03114)
Cyclin-dependent kinase 5 (EC 2.7.11.1) (Cell division protein kinase 5) (Cyclin-dependent-like kinase 5) (Serine/threonine-protein kinase PSSALRE) (Tau protein kinase II catalytic subunit) (TPKII catalytic subunit)
Gene: CDK5

Species: Rattus norvegicus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	17036052
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0030182 - neuron differentiation GO:0051402 - neuron apoptotic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1893 Rn			1 292
+	Hs
		443339 VIME_HUMAN (8-317): 1.34e-117: 382: 30.28		CDK2_HUMAN (1-292): 3.89e-144: 408: 59.39
+	Hs
		213939 KRT86_HUMAN (6-316): 8.35e-70: 245: 19.62		CDK18_HUMAN (1-286): 6.79e-108: 323: 56.60
+	Hs
		318796 K2C75_HUMAN (6-318): 5.2e-65: 233: 20.63		CDK18_HUMAN (1-286): 6.79e-108: 323: 56.60
+	Hs
		821754 NEST_HUMAN (1-954): 3.95e-36: 152: 51.65		CDK5_HUMAN (1-292): 1.02e-139: 397: 99.32
+	Hs
		625440 NUMA1_HUMAN (525-1793): 1.64e-31: 137: 10.32		CDK2_HUMAN (1-292): 3.89e-144: 408: 59.39
+	Hs
		625176 MYH9_HUMAN (800-1674): 3.68e-29: 130: 10.26		CDK2_HUMAN (1-292): 3.89e-144: 408: 59.39
+	Hs
		528401 MYH8_HUMAN (878-1613): 2.14e-26: 120: 10.83		CDK2_HUMAN (1-292): 3.89e-144: 408: 59.39
+	Hs
		960128 MYH2_HUMAN (878-1613): 1.13e-26: 122: 11.36		CDK3_HUMAN (1-291): 8.83e-142: 402: 61.30
+	Hs
		502908 MYH3_HUMAN (748-1673): 3.65e-26: 120: 11.51		CDK3_HUMAN (1-291): 8.83e-142: 402: 61.30
+	Hs
		528405 MYH8_HUMAN (878-1613): 2.14e-26: 120: 10.83		CDK3_HUMAN (1-291): 8.83e-142: 402: 61.30
+	Hs
		528368 MYH6_HUMAN (878-1665): 2.16e-25: 117: 11.00		CDK3_HUMAN (1-291): 8.83e-142: 402: 61.30
+	Hs
		522542 MYH1_HUMAN (855-1608): 6.68e-25: 116: 9.66		CDK3_HUMAN (1-291): 8.83e-142: 402: 61.30
+	Hs
		522604 MYH7_HUMAN (591-1562): 2.52e-24: 114: 12.13		CDK3_HUMAN (1-291): 8.83e-142: 402: 61.30
+	Hs
		960129 MYH13_HUMAN (868-1692): 6.61e-24: 112: 11.03		CDK3_HUMAN (1-291): 8.83e-142: 402: 61.30
+	Hs
		724717 MYH9_HUMAN (800-1674): 3.68e-29: 130: 10.26		CDK7_HUMAN (2-292): 3.41e-128: 370: 45.24
+	Hs
		414709 GFAP_HUMAN (8-317): 2.35e-22: 104: 30.99		CDK1_HUMAN (1-289): 2e-135: 386: 56.01
+	Hs
		414704 TPR_HUMAN (1-771): 2.53e-20: 101: 10.04		CDK1_HUMAN (1-289): 2e-135: 386: 56.01
+	Mm
		372930 GFAP_MOUSE (8-317): 4.97e-21: 100: 29.94		CDK1_MOUSE (1-289): 3.97e-134: 383: 56.70
+	Hs
		518840 TPR_HUMAN (1-771): 2.53e-20: 101: 10.04		CDK7_HUMAN (2-292): 3.41e-128: 370: 45.24
+	Hs
		414801 PERI_HUMAN (8-317): 9.59e-14: 77.8: 29.41		CDK1_HUMAN (1-289): 2e-135: 386: 56.01