HitPredict

Interactor 1: GNA11 (P21278)
Guanine nucleotide-binding protein subunit alpha-11 (G alpha-11) (G-protein subunit alpha-11)
Gene: GNA11

Interactor 2: AGAP2 (Q3UHD9)
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 (AGAP-2) (Centaurin-gamma-1) (Cnt-g1) (Phosphatidylinositol 3-kinase enhancer) (PIKE)
Gene: AGAP2

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	28706196
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003924 - GTPase activity GO:0005525 - GTP binding GO:0005737 - cytoplasm GO:0044877 - protein-containing complex binding GO:0046872 - metal ion binding
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 359 Mm			1 1186
+	Mm
		597633 GNAQ_MOUSE (1-359): 1.91e-168: 475: 89.14		AGAP2_MOUSE (1-1186): 0: 1024: 100.00
+	Mm
		70621 GNAI1_MOUSE (7-358): 2.42e-162: 459: 51.41		AGAP2_MOUSE (1-1186): 0: 1024: 100.00
+	Mm
		579647 GNAO_MOUSE (7-358): 7.03e-159: 450: 48.59		AGAP2_MOUSE (1-1186): 0: 1024: 100.00
+	Mm
		250851 GNAZ_MOUSE (7-358): 5.83e-145: 415: 46.20		AGAP2_MOUSE (1-1186): 0: 1024: 100.00
+	Mm
		649244 GNA13_MOUSE (8-358): 5.57e-144: 414: 45.00		AGAP2_MOUSE (1-1186): 0: 1024: 100.00
+	Mm
		926665 GNAS2_MOUSE (7-359): 1.87e-136: 395: 38.83		AGAP2_MOUSE (1-1186): 0: 1024: 100.00