HitPredict

Interactor 1: VATB2 (P21281)
V-type proton ATPase subunit B, brain isoform (V-ATPase subunit B 2) (Endomembrane proton pump 58 kDa subunit) (HO57) (Vacuolar proton pump subunit B 2)
Gene: ATP6V1B2

Interactor 2: VPP2 (Q9Y487)
V-type proton ATPase 116 kDa subunit a 2 (V-ATPase 116 kDa subunit a 2) (Lysosomal H(+)-transporting ATPase V0 subunit a 2) (TJ6) (Vacuolar proton translocating ATPase 116 kDa subunit a isoform 2)
Gene: ATP6V0A2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.74 0.60 0.667

The method score is based on:

Property Details
Experiments 28514442, 33961781, 35271311
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005765 - lysosomal membrane
GO:0005886 - plasma membrane
GO:0007035 - vacuolar acidification
GO:0016241 - regulation of macroautophagy
GO:0043231 - intracellular membrane-bounded organelle
and 2 others

more...
Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 511
Hs

1 856
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Sc
+ Sc

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Last updated: 15 Jul 2024