HitPredict

Interactor 1: PWP1 (P21304)
Periodic tryptophan protein 1
Gene: PWP1

Interactor 2: PWP1 (P21304)
Periodic tryptophan protein 1
Gene: PWP1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	1.00	0.768

Property	Details
Experiments	11967834, 14759368
Identification Methods	unspecified method, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	WD40~WD40
Common GO terms	GO:0005634 - nucleus GO:0005730 - nucleolus GO:0005737 - cytoplasm GO:0006364 - rRNA processing
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 576 Sc			1 576
+	Sc
		630844 NLE1_YEAST (206-564): 3.22e-61: 212: 13.61		NLE1_YEAST (206-564): 3.22e-61: 212: 13.61
+	Hs
		560857 GBB3_HUMAN (178-452): 5.14e-57: 196: 18.90		GBB3_HUMAN (178-452): 5.14e-57: 196: 18.90
+	Ca
		483033 TUP1_CANAL (271-561): 1.42e-49: 181: 11.29		TUP1_CANAL (271-561): 1.42e-49: 181: 11.29
+	Hs
		903174 TBL3_HUMAN (83-562): 6.27e-60: 214: 8.82		WDR5_HUMAN (365-560): 8.99e-36: 138: 14.07
+	Hs
		245546 TBL1X_HUMAN (281-559): 9.52e-45: 169: 14.24		TBL1X_HUMAN (281-559): 9.52e-45: 169: 14.24
+	Sp
		999838 TUP11_SCHPO (112-362): 1.12e-41: 161: 13.39		TUP11_SCHPO (112-362): 1.12e-41: 161: 13.39
+	Dm
		1099146 CAF1_DROME (96-469): 1.01e-38: 149: 15.17		CAF1_DROME (96-469): 1.01e-38: 149: 15.17
+	Hs
		245630 TBL1X_HUMAN (281-559): 9.52e-45: 169: 14.24		TBL1Y_HUMAN (327-561): 1.01e-27: 119: 13.25
+	Hs
		1016312 TBL3_HUMAN (83-562): 6.27e-60: 214: 8.82		SNR40_HUMAN (31-239): 3.83e-13: 72.8: 6.34
+	Hs
		245633 TBL1X_HUMAN (281-559): 9.52e-45: 169: 14.24		TBL1R_HUMAN (321-561): 3.43e-27: 117: 12.55
+	Dm
		1358845 WDS_DROME (365-560): 3.58e-36: 140: 13.57		WDS_DROME (365-560): 3.58e-36: 140: 13.57
+	Hs
		903077 WDR5_HUMAN (365-560): 8.99e-36: 138: 14.07		WDR5_HUMAN (365-560): 8.99e-36: 138: 14.07
+	Hs
		1240442 POC1A_HUMAN (224-505): 4.58e-45: 166: 15.19		POC1B_HUMAN (118-297): 5.26e-19: 92.1: 11.41
+	Hs
		903551 WDR5_HUMAN (365-560): 8.99e-36: 138: 14.07		NLE1_HUMAN (407-558): 2.17e-27: 117: 13.75
+	Hs
		903204 WDR5_HUMAN (365-560): 8.99e-36: 138: 14.07		PWP1_HUMAN (331-554): 4.52e-20: 95.6: 9.49
+	Hs
		903171 WDR5_HUMAN (365-560): 8.99e-36: 138: 14.07		RBBP4_HUMAN (330-523): 4.94e-20: 94.6: 15.05
+	Hs
		903428 WDR5_HUMAN (365-560): 8.99e-36: 138: 14.07		SNR40_HUMAN (31-239): 3.83e-13: 72.8: 6.34
+	Hs
		903349 WDR5_HUMAN (365-560): 8.99e-36: 138: 14.07		WDR5B_HUMAN (431-560): 1.02e-11: 68.2: 5.30
+	Hs
		792949 WDR5_HUMAN (365-560): 8.99e-36: 138: 14.07		LIS1_HUMAN (468-561): 5.16e-11: 66.7: 10.42