HitPredict

Interactor 1: PWP1 (P21304)
Periodic tryptophan protein 1
Gene: PWP1

Interactor 2: YTM1 (Q12024)
Ribosome biogenesis protein YTM1 (Microtubule-associated protein YTM1)
Gene: YTM1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	37968396
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	WD40~WD40
Common GO terms	GO:0005634 - nucleus GO:0005730 - nucleolus GO:0006364 - rRNA processing
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 576 Sc			1 460
+	Hs
		245633 TBL1X_HUMAN (281-559): 9.52e-45: 169: 14.24		TBL1R_HUMAN (124-457): 3.32e-68: 227: 17.43
+	Hs
		903418 WDR5_HUMAN (365-560): 8.99e-36: 138: 14.07		FBXW7_HUMAN (190-457): 6.72e-60: 209: 18.38
+	Hs
		245546 TBL1X_HUMAN (281-559): 9.52e-45: 169: 14.24		TBL1X_HUMAN (47-276): 3.39e-44: 164: 14.23
+	Hs
		245630 TBL1X_HUMAN (281-559): 9.52e-45: 169: 14.24		TBL1Y_HUMAN (47-274): 2.57e-43: 161: 13.93
+	Hs
		903174 TBL3_HUMAN (83-562): 6.27e-60: 214: 8.82		WDR5_HUMAN (362-458): 1.09e-16: 82.9: 24.49
+	Dm
		1358845 WDS_DROME (365-560): 3.58e-36: 140: 13.57		WDS_DROME (276-457): 7.66e-43: 156: 24.46
+	Hs
		1016312 TBL3_HUMAN (83-562): 6.27e-60: 214: 8.82		SNR40_HUMAN (362-459): 4.27e-15: 78.2: 18.18
+	Hs
		903349 WDR5_HUMAN (365-560): 8.99e-36: 138: 14.07		WDR5B_HUMAN (258-457): 6.29e-40: 147: 22.77
+	Sc
		630844 NLE1_YEAST (206-564): 3.22e-61: 212: 13.61		NLE1_YEAST (19-130): 2.91e-11: 67.5: 15.28
+	Ca
		483033 TUP1_CANAL (271-561): 1.42e-49: 181: 11.29		TUP1_CANAL (58-174): 3.74e-21: 97.9: 18.11
+	Hs
		792949 WDR5_HUMAN (365-560): 8.99e-36: 138: 14.07		LIS1_HUMAN (326-457): 9.83e-27: 113: 19.40
+	Dm
		1358859 WDS_DROME (365-560): 3.58e-36: 140: 13.57		FBXW7_DROME (315-458): 6e-24: 107: 18.49
+	Hs
		1240442 POC1A_HUMAN (224-505): 4.58e-45: 166: 15.19		POC1B_HUMAN (358-459): 7.69e-14: 75.2: 20.39
+	Sp
		999838 TUP11_SCHPO (112-362): 1.12e-41: 161: 13.39		TUP11_SCHPO (12-133): 6.73e-14: 75.9: 13.71
+	Hs
		903500 WDR5_HUMAN (365-560): 8.99e-36: 138: 14.07		WDR12_HUMAN (286-458): 5.45e-20: 93.7: 17.95
+	Hs
		903551 WDR5_HUMAN (365-560): 8.99e-36: 138: 14.07		NLE1_HUMAN (362-459): 3.92e-19: 91.7: 24.24
+	Hs
		209416 WDR5_HUMAN (365-560): 8.99e-36: 138: 14.07		PLRG1_HUMAN (98-249): 3.89e-17: 85.8: 13.51
+	Hs
		903077 WDR5_HUMAN (365-560): 8.99e-36: 138: 14.07		WDR5_HUMAN (362-458): 1.09e-16: 82.9: 24.49
+	Hs
		903428 WDR5_HUMAN (365-560): 8.99e-36: 138: 14.07		SNR40_HUMAN (362-459): 4.27e-15: 78.2: 18.18