HitPredict

Interactor 1: KLRG2 (A4D1S0)
Killer cell lectin-like receptor subfamily G member 2 (C-type lectin domain family 15 member B)
Gene: KLRG2

Interactor 2: LRC4B (Q9NT99)
Leucine-rich repeat-containing protein 4B (Netrin-G3 ligand) (NGL-3)
Gene: LRRC4B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.80	0.726

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	LRR_8~Lectin_C
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 409 Hs			1 713
+	Hs
		59802 KLRG2_HUMAN (1-409): 9.69e-75: 240: 100.00		LRFN1_HUMAN (31-628): 3.27e-73: 254: 21.53
+	Hs
		1166673 CLC4A_HUMAN (256-406): 8.15e-43: 151: 16.46		LRIG3_HUMAN (1-669): 4.19e-77: 270: 17.59
+	Hs
		1100734 CL12B_HUMAN (245-408): 1.12e-41: 150: 21.39		LRIG3_HUMAN (1-669): 4.19e-77: 270: 17.59
+	Hs
		644647 NKG2A_HUMAN (203-405): 1.39e-44: 156: 20.55		LRFN1_HUMAN (31-628): 3.27e-73: 254: 21.53
+	Hs
		1350024 CLC4A_HUMAN (256-406): 8.15e-43: 151: 16.46		LRFN1_HUMAN (31-628): 3.27e-73: 254: 21.53
+	Hs
		1291088 CLC4A_HUMAN (256-406): 8.15e-43: 151: 16.46		LIGO1_HUMAN (32-469): 1.17e-69: 241: 27.22
+	Hs
		1100782 CL12B_HUMAN (245-408): 1.12e-41: 150: 21.39		LIGO1_HUMAN (32-469): 1.17e-69: 241: 27.22
+	Hs
		1265939 CLC2B_HUMAN (267-407): 6.73e-45: 154: 25.00		LRFN3_HUMAN (46-599): 6.73e-65: 228: 22.19
+	Hs
		1100794 CL12B_HUMAN (245-408): 1.12e-41: 150: 21.39		LRFN3_HUMAN (46-599): 6.73e-65: 228: 22.19
+	Hs
		259512 CLC4A_HUMAN (256-406): 8.15e-43: 151: 16.46		LRRN2_HUMAN (29-502): 1.14e-63: 227: 23.24
+	Hs
		299599 CLC4E_HUMAN (271-406): 4.71e-47: 162: 18.67		LRIG2_HUMAN (13-706): 1.41e-48: 186: 15.53
+	Hs
		299573 CLC4D_HUMAN (276-405): 1.16e-44: 155: 19.72		LRIG2_HUMAN (13-706): 1.41e-48: 186: 15.53
+	Hs
		299565 CL12B_HUMAN (245-408): 1.12e-41: 150: 21.39		LRIG2_HUMAN (13-706): 1.41e-48: 186: 15.53
+	Hs
		644626 NKG2A_HUMAN (203-405): 1.39e-44: 156: 20.55		LRIG1_HUMAN (69-692): 4.88e-43: 169: 15.76
+	Hs
		1263883 CLC4D_HUMAN (276-405): 1.16e-44: 155: 19.72		LRIG1_HUMAN (69-692): 4.88e-43: 169: 15.76
+	Hs
		1100785 CL12B_HUMAN (245-408): 1.12e-41: 150: 21.39		LRIG1_HUMAN (69-692): 4.88e-43: 169: 15.76
+	Hs
		1166424 CLC4G_HUMAN (127-407): 8.03e-59: 195: 16.72		LRC4C_HUMAN (1-206): 3.43e-27: 119: 19.43
+	Hs
		1100740 CL12B_HUMAN (245-408): 1.12e-41: 150: 21.39		R4RL2_HUMAN (56-370): 1.2e-29: 124: 32.39
+	Hs
		644631 NKG2A_HUMAN (203-405): 1.39e-44: 156: 20.55		LGR4_HUMAN (66-211): 9.1e-19: 93.5: 24.83
+	Hs
		1268547 CLC4A_HUMAN (256-406): 8.15e-43: 151: 16.46		PXDN_HUMAN (9-146): 6.7e-17: 87.7: 17.61