HitPredict

Interactor 1: FLNA (P21333)
Filamin-A (FLN-A) (Actin-binding protein 280) (ABP-280) (Alpha-filamin) (Endothelial actin-binding protein) (Filamin-1) (Non-muscle filamin)
Gene: FLNA

Interactor 2: RBBP4 (Q09028)
Histone-binding protein RBBP4 (Chromatin assembly factor 1 subunit C) (CAF-1 subunit C) (Chromatin assembly factor I p48 subunit) (CAF-I 48 kDa subunit) (CAF-I p48) (Nucleosome-remodeling factor subunit RBAP48) (Retinoblastoma-binding protein 4) (RBBP-4) (Retinoblastoma-binding protein p48)
Gene: RBBP4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	37689310, 32814053
Identification Methods	proximity labelling technology, two hybrid array, two hybrid pooling approach, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 2647 Hs			1 425
+	Hs
		598140 FLNA_HUMAN (1-2647): 0: 2776: 100.00		RBBP7_HUMAN (1-425): 3.63e-115: 345: 89.20
+	Hs
		598209 FLNA_HUMAN (1-2647): 0: 2776: 100.00		WDR5B_HUMAN (92-417): 1.53e-68: 222: 18.54
+	Hs
		598240 FLNA_HUMAN (1-2647): 0: 2776: 100.00		POC1B_HUMAN (2-229): 2.56e-47: 170: 12.45
+	Hs
		598040 FLNA_HUMAN (1-2647): 0: 2776: 100.00		WDR5_HUMAN (267-425): 7.48e-35: 133: 25.61
+	Hs
		598294 FLNA_HUMAN (1-2647): 0: 2776: 100.00		GRWD1_HUMAN (263-425): 3.54e-26: 111: 23.56
+	Hs
		598345 FLNA_HUMAN (1-2647): 0: 2776: 100.00		NLE1_HUMAN (8-106): 1.77e-21: 98.3: 10.58
+	Hs
		261236 FLNB_HUMAN (28-2647): 0: 2710: 69.63		WDR5_HUMAN (267-425): 7.48e-35: 133: 25.61
+	Hs
		903137 SPTB2_HUMAN (22-460): 2.2e-118: 423: 24.62		WDR5_HUMAN (267-425): 7.48e-35: 133: 25.61