HitPredict

Interactor 1: FLNA (P21333)
Filamin-A (FLN-A) (Actin-binding protein 280) (ABP-280) (Alpha-filamin) (Endothelial actin-binding protein) (Filamin-1) (Non-muscle filamin)
Gene: FLNA

Interactor 2: PKHA4 (Q9H4M7)
Pleckstrin homology domain-containing family A member 4 (PH domain-containing family A member 4) (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1)
Gene: PLEKHA4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31091453
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2647 Hs			1 779
+	Hs
		261327 FLNB_HUMAN (28-2647): 0: 2710: 69.63		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		598170 FLNA_HUMAN (1-2647): 0: 2776: 100.00		PKHA7_HUMAN (2-440): 4.98e-50: 192: 28.02
+	Hs
		596356 FLNA_HUMAN (1-2647): 0: 2776: 100.00		RASA1_HUMAN (72-437): 2.74e-44: 174: 11.32
+	Hs
		598184 FLNA_HUMAN (1-2647): 0: 2776: 100.00		MPRIP_HUMAN (2-499): 4.76e-44: 173: 16.57
+	Hs
		598161 FLNA_HUMAN (1-2647): 0: 2776: 100.00		RHG21_HUMAN (22-662): 1.96e-43: 172: 13.18
+	Hs
		598221 FLNA_HUMAN (1-2647): 0: 2776: 100.00		RHG24_HUMAN (55-181): 6.43e-27: 119: 25.93
+	Hs
		1052940 FLNC_HUMAN (32-2647): 0: 1432: 35.96		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		963417 SPTB2_HUMAN (22-460): 2.2e-118: 423: 24.62		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		725697 ACTN2_HUMAN (6-459): 1.76e-121: 410: 23.62		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		521613 ACTN1_HUMAN (20-459): 1.14e-118: 402: 23.53		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		211664 ACTN4_HUMAN (23-382): 4.2e-112: 383: 27.01		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Mm
		1143715 SPTB2_MOUSE (22-460): 2.2e-118: 423: 24.62		CNKR2_MOUSE (1-468): 7.51e-48: 185: 14.40
+	Hs
		521561 ACTN1_HUMAN (20-459): 1.14e-118: 402: 23.53		PKHA7_HUMAN (2-440): 4.98e-50: 192: 28.02
+	Hs
		57984 ACTN3_HUMAN (30-460): 2.85e-118: 401: 25.28		A2RRN7_HUMAN (57-428): 4.21e-47: 181: 12.44
+	Hs
		993303 ACTN3_HUMAN (30-460): 2.85e-118: 401: 25.28		CAPS1_HUMAN (11-428): 3.69e-46: 180: 11.26
+	Hs
		211598 ACTN4_HUMAN (23-382): 4.2e-112: 383: 27.01		PKHA7_HUMAN (2-440): 4.98e-50: 192: 28.02
+	Hs
		963422 SPTB2_HUMAN (22-460): 2.2e-118: 423: 24.62		PKHA5_HUMAN (2-653): 1.62e-36: 150: 17.61
+	Hs
		211597 ACTN4_HUMAN (23-382): 4.2e-112: 383: 27.01		CYTSA_HUMAN (320-643): 3.92e-43: 171: 12.81
+	Hs
		521574 ACTN1_HUMAN (20-459): 1.14e-118: 402: 23.53		RHG24_HUMAN (55-181): 6.43e-27: 119: 25.93
+	Hs
		211612 ACTN4_HUMAN (23-382): 4.2e-112: 383: 27.01		RHG24_HUMAN (55-181): 6.43e-27: 119: 25.93