HitPredict

Interactor 1: FLNA (P21333)
Filamin-A (FLN-A) (Actin-binding protein 280) (ABP-280) (Alpha-filamin) (Endothelial actin-binding protein) (Filamin-1) (Non-muscle filamin)
Gene: FLNA

Interactor 2: RAI14 (Q9P0K7)
Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Novel retinal pigment epithelial cell protein) (Retinoic acid-induced protein 14)
Gene: RAI14

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 2647 Hs			1 980
+	Hs
		598255 FLNA_HUMAN (1-2647): 0: 2776: 100.00		MY18A_HUMAN (351-942): 3.03e-73: 267: 19.06
+	Hs
		261303 FLNB_HUMAN (28-2647): 0: 2710: 69.63		MY18A_HUMAN (351-942): 3.03e-73: 267: 19.06
+	Hs
		598279 FLNA_HUMAN (1-2647): 0: 2776: 100.00		EHMT2_HUMAN (57-424): 2.35e-45: 180: 14.71
+	Rn
		88611 FLNC_RAT (32-2647): 0: 1435: 36.03		ANK3_RAT (24-405): 1.07e-52: 204: 18.85
+	Hs
		1021400 FLNC_HUMAN (32-2647): 0: 1432: 35.96		ANK3_HUMAN (24-405): 2.11e-47: 187: 18.74
+	Hs
		963381 SPTB2_HUMAN (22-460): 2.2e-118: 423: 24.62		MY18A_HUMAN (351-942): 3.03e-73: 267: 19.06
+	Hs
		211632 ACTN4_HUMAN (23-382): 4.2e-112: 383: 27.01		MY18A_HUMAN (351-942): 3.03e-73: 267: 19.06
+	Hs
		963306 SPTB2_HUMAN (22-460): 2.2e-118: 423: 24.62		ANK3_HUMAN (24-405): 2.11e-47: 187: 18.74
+	Mm
		103603 SPTB2_MOUSE (22-460): 2.2e-118: 423: 24.62		ANK3_MOUSE (60-438): 3.15e-42: 170: 21.37
+	Mm
		103598 Q3UGX2_MOUSE (2-460): 6.8e-117: 418: 23.77		ANK3_MOUSE (60-438): 3.15e-42: 170: 21.37
+	Hs
		556695 SPTB2_HUMAN (22-460): 2.2e-118: 423: 24.62		ANK1_HUMAN (5-138): 7.09e-32: 137: 26.67
+	Hs
		506803 SPTB1_HUMAN (2-460): 2.89e-117: 419: 23.57		ANK1_HUMAN (5-138): 7.09e-32: 137: 26.67
+	Hs
		862027 SPTB2_HUMAN (22-460): 2.2e-118: 423: 24.62		DAPK1_HUMAN (111-426): 2.39e-29: 128: 12.03
+	Hs
		521508 ACTN1_HUMAN (20-459): 1.14e-118: 402: 23.53		DAPK1_HUMAN (111-426): 2.39e-29: 128: 12.03
+	Dr
		1186355 Q7SYE2_DANRE (6-459): 6.25e-121: 408: 24.31		MIB1_DANRE (1-158): 1.25e-21: 103: 20.96
+	Hs
		211541 ACTN4_HUMAN (23-382): 4.2e-112: 383: 27.01		DAPK1_HUMAN (111-426): 2.39e-29: 128: 12.03
+	Dr
		1103596 Q2YDR5_DANRE (18-459): 5.32e-120: 406: 23.04		MIB1_DANRE (1-158): 1.25e-21: 103: 20.96
+	Dr
		1186354 Q7SYD3_DANRE (21-459): 2.27e-119: 404: 23.74		MIB1_DANRE (1-158): 1.25e-21: 103: 20.96