Interactor 1: NF1 (P21359)
Neurofibromin (Neurofibromatosis-related protein NF-1) [Cleaved into: Neurofibromin truncated]
Gene: NF1

Interactor 2: IRF8 (Q02556)
Interferon regulatory factor 8 (IRF-8) (Interferon consensus sequence-binding protein) (H-ICSBP) (ICSBP)
Gene: IRF8

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.77 0.60 0.683

The method score is based on:

Property Details
Experiments 15371411, 16914719, 17200120, 19801548
Identification Methods anti tag coimmunoprecipitation, electrophoretic mobility shift assay
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0043065 - positive regulation of apoptotic process
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 2839
Hs

1 426
+ Mm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024