HitPredict

Interactor 1: A4D1W7 (A4D1W7)
Inhibin beta A chain (Activin beta-A chain)
Gene: INHBA

Interactor 2: AVR2B (Q13705)
Activin receptor type-2B (EC 2.7.11.30) (Activin receptor type IIB) (ACTR-IIB)
Gene: ACVR2B

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	20860622
Identification Methods	surface plasmon resonance
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Activin_recp~TGF_beta
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 426 Hs			1 512
+	Hs
		439886 INHBA_HUMAN (1-426): 6.69e-167: 477: 100.00		AVR2B_HUMAN (1-512): 1.04e-153: 450: 100.00
+	Hs
		439881 INHBA_HUMAN (1-426): 6.69e-167: 477: 100.00		AVR2A_HUMAN (3-512): 2.84e-150: 441: 67.32
+	Mm
		646088 INHBA_MOUSE (1-426): 2.24e-167: 478: 96.01		AVR2A_MOUSE (3-512): 6.08e-150: 440: 67.12
+	Mm
		646092 INHBA_MOUSE (1-426): 2.24e-167: 478: 96.01		AVR2B_MOUSE (1-512): 1.1e-147: 435: 93.66
+	Hs
		439885 INHBA_HUMAN (1-426): 6.69e-167: 477: 100.00		ACVR1_HUMAN (39-492): 3.02e-134: 400: 30.39
+	Hs
		439887 INHBA_HUMAN (1-426): 6.69e-167: 477: 100.00		BMPR2_HUMAN (4-502): 3.62e-122: 384: 33.84
+	Hs
		439883 INHBA_HUMAN (1-426): 6.69e-167: 477: 100.00		ACVL1_HUMAN (48-484): 2.28e-114: 348: 30.93
+	Hs
		439882 INHBA_HUMAN (1-426): 6.69e-167: 477: 100.00		ACV1B_HUMAN (3-481): 6.79e-110: 337: 28.88
+	Mm
		982854 INHBA_MOUSE (1-426): 2.24e-167: 478: 96.01		ACV1B_MOUSE (3-481): 4.67e-109: 335: 29.47
+	Hs
		574203 BMP7_HUMAN (48-425): 3.22e-108: 327: 19.46		AVR2B_HUMAN (1-512): 1.04e-153: 450: 100.00
+	Hs
		451820 INHBB_HUMAN (31-426): 2.64e-106: 321: 41.35		AVR2B_HUMAN (1-512): 1.04e-153: 450: 100.00
+	Hs
		574181 BMP7_HUMAN (48-425): 3.22e-108: 327: 19.46		AVR2A_HUMAN (3-512): 2.84e-150: 441: 67.32
+	Hs
		451817 INHBB_HUMAN (31-426): 2.64e-106: 321: 41.35		AVR2A_HUMAN (3-512): 2.84e-150: 441: 67.32
+	Hs
		574199 BMP7_HUMAN (48-425): 3.22e-108: 327: 19.46		ACVR1_HUMAN (39-492): 3.02e-134: 400: 30.39
+	Hs
		574204 BMP7_HUMAN (48-425): 3.22e-108: 327: 19.46		BMPR2_HUMAN (4-502): 3.62e-122: 384: 33.84
+	Hs
		122282 BMP7_HUMAN (48-425): 3.22e-108: 327: 19.46		BMR1B_HUMAN (58-486): 1.94e-126: 380: 32.39
+	Hs
		451821 INHBB_HUMAN (31-426): 2.64e-106: 321: 41.35		BMPR2_HUMAN (4-502): 3.62e-122: 384: 33.84
+	Hs
		122280 BMP2_HUMAN (26-425): 1.11e-104: 317: 23.59		BMR1B_HUMAN (58-486): 1.94e-126: 380: 32.39
+	Hs
		574186 BMP7_HUMAN (48-425): 3.22e-108: 327: 19.46		BMR1A_HUMAN (58-486): 1.16e-117: 358: 30.02
+	Hs
		451818 INHBB_HUMAN (31-426): 2.64e-106: 321: 41.35		ACV1B_HUMAN (3-481): 6.79e-110: 337: 28.88