Interactor 1: ISY1 (P21374)
Pre-mRNA-splicing factor ISY1 (Interactor of SYF1) (PRP19-associated complex protein 30)
Gene: ISY1

Interactor 2: CEF1 (Q03654)
Pre-mRNA-splicing factor CEF1 (PRP nineteen-associated complex protein 85) (PRP19-associated complex protein 85)
Gene: CEF1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.81 0.60 0.698

The method score is based on:

Property Details
Experiments 11102353, 11884590, 30879786, 37968396
Identification Methods two hybrid, coimmunoprecipitation, affinity chromatography technology, biochemical, pull down, tandem affinity purification
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000350 - generation of catalytic spliceosome for second transesterification step
GO:0000974 - Prp19 complex
GO:0005737 - cytoplasm
GO:0071006 - U2-type catalytic step 1 spliceosome
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 235
Sc

1 590
+ Hs
+ Sp

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024