HitPredict

Interactor 1: S1PR1 (P21453)
Sphingosine 1-phosphate receptor 1 (S1P receptor 1) (S1P1) (Endothelial differentiation G-protein coupled receptor 1) (Sphingosine 1-phosphate receptor Edg-1) (S1P receptor Edg-1) (CD antigen CD363)
Gene: S1PR1

Interactor 2: GNAI1 (P63096)
Guanine nucleotide-binding protein G(i) subunit alpha-1 (Adenylate cyclase-inhibiting G alpha protein)
Gene: GNAI1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.54 1.00 0.740

The method score is based on:

Property Details
Experiments 8626678
Identification Methods affinity chromatography technology, pull down, two hybrid
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains 7tm_1~G-alpha
Common GO terms GO:0001664 - G protein-coupled receptor binding
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0007186 - G protein-coupled receptor signaling pathway
and 1 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 382
Hs

1 354
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Bt
+ Hs
+ Hs
+ Hs
+ Ss
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024