HitPredict

Interactor 1: S1PR1 (P21453)
Sphingosine 1-phosphate receptor 1 (S1P receptor 1) (S1P1) (Endothelial differentiation G-protein coupled receptor 1) (Sphingosine 1-phosphate receptor Edg-1) (S1P receptor Edg-1) (CD antigen CD363)
Gene: S1PR1

Interactor 2: CKLF6 (Q9NX76)
CKLF-like MARVEL transmembrane domain-containing protein 6 (Chemokine-like factor superfamily member 6)
Gene: CMTM6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 382 Hs			1 183
+	Hs
		1268673 LPAR1_HUMAN (23-342): 6.22e-89: 274: 38.51		CKLF6_HUMAN (1-183): 8.08e-62: 191: 100.00
+	Hs
		1224733 LPAR1_HUMAN (23-342): 6.22e-89: 274: 38.51		CKLF4_HUMAN (7-182): 1.12e-53: 172: 34.66
+	Hs
		328405 S1PR4_HUMAN (1-329): 2.24e-81: 255: 39.76		CKLF6_HUMAN (1-183): 8.08e-62: 191: 100.00
+	Hs
		1335596 LPAR2_HUMAN (23-365): 5.55e-76: 240: 34.88		CKLF6_HUMAN (1-183): 8.08e-62: 191: 100.00
+	Hs
		686644 CCR1_HUMAN (27-360): 7.95e-64: 209: 14.29		PLP2_HUMAN (33-183): 1.41e-40: 136: 19.87