HitPredict

Interactor 1: ZNF10 (P21506)
Zinc finger protein 10 (Zinc finger protein KOX1)
Gene: ZNF10

Interactor 2: TIF1B (Q13263)
Transcription intermediary factor 1-beta (TIF1-beta) (E3 SUMO-protein ligase TRIM28) (EC 2.3.2.27) (KRAB-associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (Nuclear corepressor KAP-1) (RING finger protein 96) (RING-type E3 ubiquitin transferase TIF1-beta) (Tripartite motif-containing protein 28)
Gene: TRIM28

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.95	0.60	0.759

Property	Details
Experiments	31856708, 35162997, 10653693, 10022127, 9016654, 10748030, 19850934, 20176155, 21170338, 17512541, 8769649, 35271311
Identification Methods	affinity chromatography technology, two hybrid, pull down, biochemical, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0032991 - protein-containing complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 573 Hs			1 835
+	Hs
		64159 ZN726_HUMAN (12-568): 0: 729: 37.07		TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00
+	Hs
		1029826 ZN471_HUMAN (1-572): 0: 701: 38.50		TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00
+	Hs
		1029788 ZN184_HUMAN (55-569): 0: 687: 38.29		TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00
+	Hs
		1029490 ZN699_HUMAN (3-571): 0: 682: 37.22		TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00
+	Hs
		977985 ZNF90_HUMAN (12-573): 0: 674: 36.99		TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00
+	Hs
		1029645 ZN527_HUMAN (1-570): 0: 664: 40.86		TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00
+	Hs
		1029501 Z585B_HUMAN (71-573): 0: 653: 38.58		TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00
+	Hs
		1029756 Z354B_HUMAN (1-570): 0: 648: 39.25		TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00
+	Hs
		1029965 ZN624_HUMAN (11-573): 0: 644: 43.29		TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00
+	Hs
		240840 Z354A_HUMAN (1-572): 0: 644: 39.84		TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00
+	Hs
		970658 ZNF45_HUMAN (61-570): 0: 637: 37.96		TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00
+	Hs
		983756 ZNF91_HUMAN (54-568): 0: 635: 36.95		TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00
+	Hs
		549159 ZN250_HUMAN (1-569): 0: 626: 41.28		TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00
+	Hs
		1029899 ZN160_HUMAN (7-573): 0: 616: 38.33		TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00
+	Hs
		64157 ZN726_HUMAN (12-568): 0: 729: 37.07		TIF1A_HUMAN (404-808): 1.31e-52: 200: 21.55
+	Hs
		170255 ZNF10_HUMAN (1-573): 0: 685: 100.00		TIF1A_HUMAN (404-808): 1.31e-52: 200: 21.55
+	Hs
		549240 ZN250_HUMAN (1-569): 0: 626: 41.28		TRIM1_HUMAN (40-589): 4.03e-64: 231: 15.36
+	Hs
		549143 ZN250_HUMAN (1-569): 0: 626: 41.28		TRI23_HUMAN (38-421): 2.37e-56: 205: 14.42
+	Hs
		563803 ZNF43_HUMAN (55-546): 0: 622: 36.45		TRI33_HUMAN (406-826): 1.6e-54: 206: 19.32
+	Hs
		170388 ZN484_HUMAN (7-573): 0: 613: 33.72		TIF1A_HUMAN (404-808): 1.31e-52: 200: 21.55