HitPredict

Interactor 1: SH321 (A4FU49)
SH3 domain-containing protein 21
Gene: SH3D21

Interactor 2: YAP1 (P46937)
Transcriptional coactivator YAP1 (Yes-associated protein 1) (Protein yorkie homolog) (Yes-associated protein YAP65 homolog)
Gene: YAP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	35044719
Identification Methods	unspecified method, phage display
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 640 Hs			1 504
+	Hs
		1049723 ARHG7_HUMAN (26-604): 1e-49: 187: 13.67		ITCH_HUMAN (3-504): 3.59e-121: 378: 15.17
+	Hs
		1294845 SH3G2_HUMAN (3-127): 3.5e-29: 121: 26.40		ITCH_HUMAN (3-504): 3.59e-121: 378: 15.17
+	Hs
		1294844 SH3G1_HUMAN (3-127): 7.04e-28: 117: 24.00		ITCH_HUMAN (3-504): 3.59e-121: 378: 15.17
+	Hs
		125348 GRB2_HUMAN (44-127): 7.52e-21: 93.3: 33.33		WWP2_HUMAN (12-504): 8.56e-129: 397: 16.54
+	Hs
		1294846 SH3G3_HUMAN (2-129): 3.24e-24: 106: 24.22		ITCH_HUMAN (3-504): 3.59e-121: 378: 15.17
+	Hs
		808883 SH3G1_HUMAN (3-127): 7.04e-28: 117: 24.00		YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00
+	Hs
		125051 GRAP2_HUMAN (58-123): 1.42e-13: 74.3: 34.85		WWP2_HUMAN (12-504): 8.56e-129: 397: 16.54
+	Hs
		808609 MDC1_HUMAN (117-639): 6.33e-24: 109: 9.96		YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00
+	Hs
		275221 GRAP2_HUMAN (58-123): 1.42e-13: 74.3: 34.85		ITCH_HUMAN (3-504): 3.59e-121: 378: 15.17
+	Hs
		809059 CD2AP_HUMAN (18-386): 4.23e-16: 84: 15.18		YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00
+	Sc
		765401 PIN3_YEAST (63-123): 2.4e-12: 68.5: 34.43		RSP5_YEAST (3-504): 1.79e-105: 334: 15.25
+	Hs
		253399 SRGP2_HUMAN (1-439): 1.37e-35: 146: 14.09		MAGI1_HUMAN (69-305): 1.87e-39: 155: 18.32
+	Hs
		1326808 CD2AP_HUMAN (18-386): 4.23e-16: 84: 15.18		WWTR1_HUMAN (51-504): 2.59e-59: 202: 39.83
+	Sc
		975839 PIN3_YEAST (63-123): 2.4e-12: 68.5: 34.43		TOM1_YEAST (261-504): 2.18e-46: 176: 11.34
+	Hs
		924608 GRB2_HUMAN (44-127): 7.52e-21: 93.3: 33.33		Q1RLN5_HUMAN (5-284): 5.87e-38: 150: 17.54
+	Hs
		1256274 SH3R3_HUMAN (9-567): 1.84e-11: 69.6: 11.11		MAGI1_HUMAN (69-305): 1.87e-39: 155: 18.32