HitPredict

Interactor 1: VPS1 (P21576)
Vacuolar protein sorting-associated protein 1
Gene: VPS1

Interactor 2: RV167 (P39743)
Reduced viability upon starvation protein 167
Gene: RVS167

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.63	0.60	0.619

Property	Details
Experiments	26711254, 22082017
Identification Methods	protein complementation assay, two hybrid, fluorescent resonance energy transfer
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0006897 - endocytosis GO:0030479 - actin cortical patch GO:0060988 - lipid tube assembly
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 704 Sc			1 482
+	Hs
		128646 DNM1L_HUMAN (3-704): 0: 737: 39.58		SHLB2_HUMAN (85-481): 5.21e-40: 150: 12.34
+	Hs
		128631 DNM1L_HUMAN (3-704): 0: 737: 39.58		SH3G1_HUMAN (85-480): 2.12e-38: 145: 12.78
+	Mm
		139028 DYN1_MOUSE (3-636): 0: 681: 40.13		BIN1_MOUSE (3-481): 3.2e-49: 179: 13.71
+	Hs
		131238 DYN1_HUMAN (3-636): 0: 679: 40.13		BIN1_HUMAN (3-481): 3.89e-49: 179: 12.67
+	Hs
		983417 DYN1_HUMAN (3-636): 0: 679: 40.13		PACN2_HUMAN (5-481): 2.54e-49: 177: 15.28
+	Rn
		139987 DYN1_RAT (3-636): 0: 672: 39.97		BIN1_RAT (3-481): 5.26e-49: 178: 13.71
+	Hs
		983372 DYN1_HUMAN (3-636): 0: 679: 40.13		MYO1E_HUMAN (5-480): 8.88e-45: 170: 14.14
+	Mm
		760454 DYN1_MOUSE (3-636): 0: 681: 40.13		SH3G2_MOUSE (84-480): 8.19e-39: 146: 14.75
+	Mm
		760453 DYN1_MOUSE (3-636): 0: 681: 40.13		SH3G1_MOUSE (85-480): 1.53e-38: 145: 12.28
+	Hs
		983405 DYN1_HUMAN (3-636): 0: 679: 40.13		SH3G2_HUMAN (84-480): 7.48e-39: 146: 14.25
+	Hs
		983404 DYN1_HUMAN (3-636): 0: 679: 40.13		SH3G1_HUMAN (85-480): 2.12e-38: 145: 12.78
+	Rn
		599414 DYN1_RAT (3-636): 0: 672: 39.97		PACN1_RAT (5-480): 8.96e-39: 148: 13.40
+	Rn
		192351 DYN1_RAT (3-636): 0: 672: 39.97		SH3G2_RAT (84-480): 4.97e-39: 146: 15.00
+	Rn
		193636 DYN1_RAT (3-636): 0: 672: 39.97		SH3G1_RAT (85-480): 3.18e-38: 144: 12.53
+	Mm
		760469 DYN1_MOUSE (3-636): 0: 681: 40.13		ITSN1_MOUSE (192-482): 2.49e-18: 90.6: 17.32
+	Hs
		983379 DYN1_HUMAN (3-636): 0: 679: 40.13		ITSN1_HUMAN (192-482): 9.15e-19: 91.8: 16.67
+	Rn
		599413 DYN1_RAT (3-636): 0: 672: 39.97		ITSN1_RAT (192-482): 4.88e-18: 89.9: 17.32
+	Mm
		760459 DYN1_MOUSE (3-636): 0: 681: 40.13		AMPH_MOUSE (300-481): 3.06e-10: 64.5: 12.82
+	Hs
		827736 DYN1_HUMAN (3-636): 0: 679: 40.13		AMPH_HUMAN (319-481): 1.86e-10: 65.2: 15.34
+	Rn
		139973 DYN1_RAT (3-636): 0: 672: 39.97		AMPH_RAT (290-481): 1.57e-09: 62.1: 14.35