Interactor 1: TNAP3 (P21580)
Tumor necrosis factor alpha-induced protein 3 (TNF alpha-induced protein 3) (EC 2.3.2.-) (EC 3.4.19.12) (OTU domain-containing protein 7C) (Putative DNA-binding protein A20) (Zinc finger protein A20) [Cleaved into: A20p50; A20p37]
Gene: TNFAIP3

Interactor 2: TNAP3 (P21580)
Tumor necrosis factor alpha-induced protein 3 (TNF alpha-induced protein 3) (EC 2.3.2.-) (EC 3.4.19.12) (OTU domain-containing protein 7C) (Putative DNA-binding protein A20) (Zinc finger protein A20) [Cleaved into: A20p50; A20p37]
Gene: TNFAIP3

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.983

The method score is based on:

Property Details
Experiments 25165885, 15258597, 25416956, 28244869, 30561431, 32296183, 8692885, 8797804, 11389905, 24008839, 25502805, 31515488, unassigned1304
Identification Methods two hybrid, pull down, enzymatic study, affinity chromatography technology, two hybrid array, virotrap, validated two hybrid, two hybrid prey pooling approach, coimmunoprecipitation
Interaction Type direct interaction, physical association, ubiquitination reaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains OTU~OTU
Common GO terms GO:0001922 - B-1 B cell homeostasis
GO:0002020 - protease binding
GO:0002237 - response to molecule of bacterial origin
GO:0002634 - regulation of germinal center formation
GO:0002677 - negative regulation of chronic inflammatory response
and 57 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 790
Hs

1 790
+ Mm
+ Hs
+ Hs
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024