Interactor 1: TNAP3 (P21580)
Tumor necrosis factor alpha-induced protein 3 (TNF alpha-induced protein 3) (EC 2.3.2.-) (EC 3.4.19.12) (OTU domain-containing protein 7C) (Putative DNA-binding protein A20) (Zinc finger protein A20) [Cleaved into: A20p50; A20p37]
Gene: TNFAIP3

Interactor 2: TAXB1 (Q86VP1)
Tax1-binding protein 1 (TRAF6-binding protein)
Gene: TAX1BP1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 0.60 0.758

The method score is based on:

Property Details
Experiments 32296183, 10435631, 28514442, 30561431, 33961781, 34454289, 11389905, 23018911, 18239685, 18246070, unassigned1304
Identification Methods two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation, virotrap, two hybrid prey pooling approach, two hybrid array, validated two hybrid, coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005829 - cytosol
GO:0006915 - apoptotic process
GO:0019900 - kinase binding
GO:0032088 - negative regulation of NF-kappaB transcription factor activity
GO:0034144 - negative regulation of toll-like receptor 4 signaling pathway
and 1 others

more...

Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 790
Hs

1 789
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Last updated: 15 Jul 2024