Interactor 1: RIR3 (P21672)
Ribonucleoside-diphosphate reductase large chain 2 (EC 1.17.4.1) (Ribonucleotide reductase DNA damage-inducible regulatory subunit 2) (Ribonucleotide reductase R1 subunit 2) (Ribonucleotide reductase large subunit 2)
Gene: RNR3

Interactor 2: RIR4 (P49723)
Ribonucleoside-diphosphate reductase small chain 2 (EC 1.17.4.1) (Ribonucleotide reductase R2 subunit 2) (Ribonucleotide reductase small subunit 2)
Gene: RNR4

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 37968396
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains ATP-cone~Ribonuc_red_sm, Ribonuc_red_lgC~Ribonuc_red_sm
Common GO terms GO:0004748 - ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
GO:0005737 - cytoplasm
GO:0005971 - ribonucleoside-diphosphate reductase complex
GO:0009263 - deoxyribonucleotide biosynthetic process
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 869
Sc

1 345
+ Sc
+ Sc
+ Mm
+ Sp
+ Hs
+ Hs
+ Vv
+ Hh
+ Ec
+ Hh
+ Hh
+ Ha
+ Mp

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024