Interactor 1: TAF1 (P21675)
Transcription initiation factor TFIID subunit 1 (EC 2.3.1.48) (EC 2.7.11.1) (Cell cycle gene 1 protein) (TBP-associated factor 250 kDa) (p250) (Transcription initiation factor TFIID 250 kDa subunit) (TAF(II)250) (TAFII-250) (TAFII250)
Gene: TAF1

Interactor 2: TAF1 (P21675)
Transcription initiation factor TFIID subunit 1 (EC 2.3.1.48) (EC 2.7.11.1) (Cell cycle gene 1 protein) (TBP-associated factor 250 kDa) (p250) (Transcription initiation factor TFIID 250 kDa subunit) (TAF(II)250) (TAFII-250) (TAFII250)
Gene: TAF1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 29111974
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Bromodomain~Bromodomain, DUF3591~DUF3591, DUF3591~TBP-binding
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000209 - protein polyubiquitination
GO:0000785 - chromatin
GO:0000979 - RNA polymerase II core promoter sequence-specific DNA binding
GO:0001091 - RNA polymerase II general transcription initiation factor binding
and 48 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 1893
Hs

1 1893
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+ Dm
+ Sc
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+ Sp
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024