HitPredict

Interactor 1: TAF1 (P21675)
Transcription initiation factor TFIID subunit 1 (EC 2.3.1.48) (EC 2.7.11.1) (Cell cycle gene 1 protein) (TBP-associated factor 250 kDa) (p250) (Transcription initiation factor TFIID 250 kDa subunit) (TAF(II)250) (TAFII-250) (TAFII250)
Gene: TAF1

Interactor 2: ELK3 (P41970)
ETS domain-containing protein Elk-3 (ETS-related protein ERP) (ETS-related protein NET) (Serum response factor accessory protein 2) (SAP-2) (SRF accessory protein 2)
Gene: ELK3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1893 Hs			1 407
+	Hs
		600090 TAF1_HUMAN (1-1893): 0: 2001: 100.00		ELF1_HUMAN (4-377): 1.93e-37: 145: 20.78
+	Hs
		600213 TAF1_HUMAN (1-1893): 0: 2001: 100.00		FEV_HUMAN (3-174): 3.76e-34: 129: 32.96
+	Hs
		987759 EP300_HUMAN (957-1700): 2.05e-99: 359: 11.98		GABPA_HUMAN (2-137): 6.47e-48: 171: 42.65
+	Hs
		542006 EP300_HUMAN (957-1700): 2.05e-99: 359: 11.98		ETS1_HUMAN (3-111): 1.03e-45: 164: 45.87
+	Hs
		542741 EP300_HUMAN (957-1700): 2.05e-99: 359: 11.98		ETS2_HUMAN (3-111): 9.5e-45: 162: 46.79
+	Hs
		781139 EP300_HUMAN (957-1700): 2.05e-99: 359: 11.98		ETV5_HUMAN (3-119): 5.53e-42: 156: 47.01
+	Hs
		794535 EP300_HUMAN (957-1700): 2.05e-99: 359: 11.98		ETV4_HUMAN (3-143): 9.93e-42: 155: 40.82
+	Mm
		70899 EP300_MOUSE (957-1700): 9.41e-100: 360: 12.13		ETV4_MOUSE (3-144): 6.05e-41: 153: 41.50
+	Hs
		584244 EP300_HUMAN (957-1700): 2.05e-99: 359: 11.98		ELK1_HUMAN (1-406): 1.68e-37: 142: 33.26
+	Hs
		840433 EP300_HUMAN (957-1700): 2.05e-99: 359: 11.98		ETV1_HUMAN (3-124): 5.12e-37: 142: 45.90
+	Mm
		101434 F8VPR5_MOUSE (954-1707): 1.45e-90: 331: 12.52		GABPA_MOUSE (2-133): 3.23e-47: 169: 44.70
+	Mm
		649230 CBP_MOUSE (954-1707): 7.55e-91: 332: 12.52		ETS1_MOUSE (3-110): 3.44e-45: 163: 46.30
+	Mm
		101425 F8VPR5_MOUSE (954-1707): 1.45e-90: 331: 12.52		ETS1_MOUSE (3-110): 3.44e-45: 163: 46.30
+	Mm
		542771 CBP_MOUSE (954-1707): 7.55e-91: 332: 12.52		ETS2_MOUSE (3-111): 9.24e-45: 162: 46.79
+	Mm
		101419 F8VPR5_MOUSE (954-1707): 1.45e-90: 331: 12.52		ETS2_MOUSE (3-111): 9.24e-45: 162: 46.79
+	Hs
		944608 EP300_HUMAN (957-1700): 2.05e-99: 359: 11.98		ELF3_HUMAN (5-87): 4.1e-34: 132: 43.53
+	Hs
		999010 EP300_HUMAN (957-1700): 2.05e-99: 359: 11.98		FEV_HUMAN (3-174): 3.76e-34: 129: 32.96
+	Hs
		507409 EP300_HUMAN (957-1700): 2.05e-99: 359: 11.98		ERG_HUMAN (3-164): 1.27e-31: 127: 37.58
+	Hs
		999200 EP300_HUMAN (957-1700): 2.05e-99: 359: 11.98		ELF5_HUMAN (6-87): 1.07e-32: 125: 41.67
+	Hs
		507480 CBP_HUMAN (954-1707): 2.54e-87: 320: 11.69		ERG_HUMAN (3-164): 1.27e-31: 127: 37.58