HitPredict

Interactor 1: TAF1 (P21675)
Transcription initiation factor TFIID subunit 1 (EC 2.3.1.48) (EC 2.7.11.1) (Cell cycle gene 1 protein) (TBP-associated factor 250 kDa) (p250) (Transcription initiation factor TFIID 250 kDa subunit) (TAF(II)250) (TAFII-250) (TAFII250)
Gene: TAF1

Interactor 2: H4 (P62805)
Histone H4
Gene: H4C1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.77	0.60	0.683

Property	Details
Experiments	34056863, 20393127, 27248496, 14731392
Identification Methods	affinity chromatography technology, pull down, fluorescent resonance energy transfer, unspecified method
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0046982 - protein heterodimerization activity
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1893 Hs			1 103
+	Hs
		917576 TAF1L_HUMAN (1-1787): 0: 1902: 93.17		H4_HUMAN (1-103): 1.38e-48: 151: 100.00
+	Sc
		356557 TAF1_YEAST (391-1229): 0: 662: 24.54		H4_YEAST (18-103): 6.13e-41: 132: 90.70
+	Hs
		917170 EP300_HUMAN (957-1700): 2.05e-99: 359: 11.98		H4_HUMAN (1-103): 1.38e-48: 151: 100.00
+	Hs
		999008 EP300_HUMAN (957-1700): 2.05e-99: 359: 11.98		H4G_HUMAN (1-98): 1.04e-38: 126: 84.69
+	Hs
		917684 CBP_HUMAN (954-1707): 2.54e-87: 320: 11.69		H4_HUMAN (1-103): 1.38e-48: 151: 100.00
+	Hs
		917657 PHIP_HUMAN (1375-1888): 1.89e-72: 271: 14.44		H4_HUMAN (1-103): 1.38e-48: 151: 100.00
+	Hs
		917466 BRWD3_HUMAN (1328-1825): 4.78e-59: 228: 12.78		H4_HUMAN (1-103): 1.38e-48: 151: 100.00
+	Dm
		950422 NU301_DROME (1169-1632): 8.06e-53: 207: 14.31		H4_DROME (1-103): 4.51e-48: 150: 99.03
+	Hs
		917517 PB1_HUMAN (1363-1685): 4.04e-51: 201: 18.26		H4_HUMAN (1-103): 1.38e-48: 151: 100.00
+	Sc
		356667 RSC4_YEAST (1350-1638): 7.86e-44: 172: 20.78		H4_YEAST (18-103): 6.13e-41: 132: 90.70
+	Hs
		918100 BAZ2B_HUMAN (1495-1630): 8.27e-32: 139: 27.21		H4_HUMAN (1-103): 1.38e-48: 151: 100.00
+	Hs
		917689 KAT2B_HUMAN (1392-1504): 3.93e-32: 138: 29.20		H4_HUMAN (1-103): 1.38e-48: 151: 100.00
+	Hs
		918101 BAZ2A_HUMAN (1506-1631): 4.55e-31: 136: 22.22		H4_HUMAN (1-103): 1.38e-48: 151: 100.00
+	Hs
		917999 BAZ1A_HUMAN (1078-1649): 3.96e-29: 130: 13.99		H4_HUMAN (1-103): 1.38e-48: 151: 100.00
+	Sp
		448934 GCN5_SCHPO (1395-1506): 7.27e-36: 145: 30.36		H4_SCHPO (18-103): 4.87e-42: 135: 89.54
+	Hs
		917688 KAT2A_HUMAN (1392-1504): 1.96e-29: 129: 29.20		H4_HUMAN (1-103): 1.38e-48: 151: 100.00
+	Hs
		918102 BAZ1B_HUMAN (1518-1668): 6.99e-28: 125: 19.21		H4_HUMAN (1-103): 1.38e-48: 151: 100.00
+	Sc
		356398 BDF1_YEAST (1164-1506): 3.83e-28: 124: 10.90		H4_YEAST (18-103): 6.13e-41: 132: 90.70
+	Sp
		448927 YK82_SCHPO (1308-1696): 5.11e-27: 121: 16.37		H4_SCHPO (18-103): 4.87e-42: 135: 89.54
+	Hs
		1271442 KAT2A_HUMAN (1392-1504): 1.96e-29: 129: 29.20		H4G_HUMAN (1-98): 1.04e-38: 126: 84.69