HitPredict

Interactor 1: TAF1 (P21675)
Transcription initiation factor TFIID subunit 1 (EC 2.3.1.48) (EC 2.7.11.1) (Cell cycle gene 1 protein) (TBP-associated factor 250 kDa) (p250) (Transcription initiation factor TFIID 250 kDa subunit) (TAF(II)250) (TAFII-250) (TAFII250)
Gene: TAF1

Interactor 2: PHIP (Q8WWQ0)
PH-interacting protein (PHIP) (DDB1- and CUL4-associated factor 14) (IRS-1 PH domain-binding protein) (WD repeat-containing protein 11)
Gene: PHIP

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31753913
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Bromodomain~Bromodomain
Common GO terms	GO:0005634 - nucleus GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0070577 - lysine-acetylated histone binding
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 1893 Hs			1 1821
+	Hs
		600117 TAF1_HUMAN (1-1893): 0: 2001: 100.00		WDR5_HUMAN (352-664): 2.63e-65: 227: 16.62
+	Hs
		600242 TAF1_HUMAN (1-1893): 0: 2001: 100.00		BRWD1_HUMAN (1-298): 6.14e-41: 168: 15.76
+	Hs
		600146 TAF1_HUMAN (1-1893): 0: 2001: 100.00		TAF5_HUMAN (161-392): 4.53e-18: 92.8: 28.33
+	Hs
		164439 TRI66_HUMAN (986-1703): 3.33e-67: 253: 11.65		PHIP_HUMAN (1-1821): 0: 1502: 100.00
+	Sc
		728715 TAF1_YEAST (391-1229): 0: 662: 24.54		BDF1_YEAST (1262-1490): 1.35e-23: 110: 20.78
+	Sc
		744640 TAF1_YEAST (391-1229): 0: 662: 24.54		TAF5_YEAST (181-311): 6.96e-09: 63.2: 32.58
+	Hs
		903172 EP300_HUMAN (957-1700): 2.05e-99: 359: 11.98		WDR5_HUMAN (352-664): 2.63e-65: 227: 16.62
+	Hs
		903405 CBP_HUMAN (954-1707): 2.54e-87: 320: 11.69		WDR5_HUMAN (352-664): 2.63e-65: 227: 16.62
+	Hs
		1199169 PHIP_HUMAN (1375-1888): 1.89e-72: 271: 14.44		PB1_HUMAN (1116-1652): 2.52e-41: 169: 15.22
+	Hs
		1164179 PHIP_HUMAN (1375-1888): 1.89e-72: 271: 14.44		BRWD3_HUMAN (1-298): 2.1e-39: 163: 13.65
+	Hs
		1199218 TRI33_HUMAN (1113-1671): 3.28e-64: 242: 12.83		PB1_HUMAN (1116-1652): 2.52e-41: 169: 15.22
+	Hs
		1164185 BRWD3_HUMAN (1328-1825): 4.78e-59: 228: 12.78		BRWD1_HUMAN (1-298): 6.14e-41: 168: 15.76
+	Hs
		1074799 PHIP_HUMAN (1375-1888): 1.89e-72: 271: 14.44		TAF5_HUMAN (161-392): 4.53e-18: 92.8: 28.33
+	Hs
		1288368 BAZ2B_HUMAN (1495-1630): 8.27e-32: 139: 27.21		SNR40_HUMAN (355-666): 5.05e-55: 198: 13.23
+	Sc
		728741 RSC4_YEAST (1350-1638): 7.86e-44: 172: 20.78		BDF1_YEAST (1262-1490): 1.35e-23: 110: 20.78
+	Sc
		744671 RSC4_YEAST (1350-1638): 7.86e-44: 172: 20.78		TAF5_YEAST (181-311): 6.96e-09: 63.2: 32.58
+	Hs
		1346964 BAZ2B_HUMAN (1495-1630): 8.27e-32: 139: 27.21		NLE1_HUMAN (1-79): 1.4e-13: 77.6: 12.66
+	Hs
		267784 KAT2B_HUMAN (1392-1504): 3.93e-32: 138: 29.20		TAF5L_HUMAN (260-496): 8.94e-09: 62.4: 26.16