HitPredict

Interactor 1: TAF1 (P21675)
Transcription initiation factor TFIID subunit 1 (EC 2.3.1.48) (EC 2.7.11.1) (Cell cycle gene 1 protein) (TBP-associated factor 250 kDa) (p250) (Transcription initiation factor TFIID 250 kDa subunit) (TAF(II)250) (TAFII-250) (TAFII250)
Gene: TAF1

Interactor 2: BRWD1 (Q9NSI6)
Bromodomain and WD repeat-containing protein 1 (WD repeat-containing protein 9)
Gene: BRWD1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	1.00	0.698

Property	Details
Experiments	35914814
Identification Methods	two hybrid, two hybrid fragment pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	Bromodomain~Bromodomain
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1893 Hs			1 2320
+	Hs
		600197 TAF1_HUMAN (1-1893): 0: 2001: 100.00		PHIP_HUMAN (5-1763): 0: 1192: 51.13
+	Hs
		600117 TAF1_HUMAN (1-1893): 0: 2001: 100.00		WDR5_HUMAN (399-710): 1.44e-45: 170: 12.38
+	Hs
		600146 TAF1_HUMAN (1-1893): 0: 2001: 100.00		TAF5_HUMAN (184-387): 1.87e-10: 68.6: 25.60
+	Hs
		1164185 BRWD3_HUMAN (1328-1825): 4.78e-59: 228: 12.78		BRWD1_HUMAN (1-2320): 0: 1633: 100.00
+	Hs
		1164179 PHIP_HUMAN (1375-1888): 1.89e-72: 271: 14.44		BRWD3_HUMAN (12-1573): 0: 1183: 58.21
+	Hs
		164439 TRI66_HUMAN (986-1703): 3.33e-67: 253: 11.65		PHIP_HUMAN (5-1763): 0: 1192: 51.13
+	Hs
		1199169 PB1_HUMAN (1363-1685): 4.04e-51: 201: 18.26		PHIP_HUMAN (5-1763): 0: 1192: 51.13
+	Hs
		903172 EP300_HUMAN (957-1700): 2.05e-99: 359: 11.98		WDR5_HUMAN (399-710): 1.44e-45: 170: 12.38
+	Hs
		903405 CBP_HUMAN (954-1707): 2.54e-87: 320: 11.69		WDR5_HUMAN (399-710): 1.44e-45: 170: 12.38
+	Hs
		1346964 BAZ2B_HUMAN (1495-1630): 8.27e-32: 139: 27.21		NLE1_HUMAN (411-764): 5.52e-59: 214: 11.72
+	Hs
		1346965 BAZ2A_HUMAN (1506-1631): 4.55e-31: 136: 22.22		NLE1_HUMAN (411-764): 5.52e-59: 214: 11.72
+	Hs
		1074799 PHIP_HUMAN (1375-1888): 1.89e-72: 271: 14.44		TAF5_HUMAN (184-387): 1.87e-10: 68.6: 25.60
+	Dm
		1358857 Q9VTZ1_DROME (1366-1504): 1.92e-27: 123: 29.79		WDS_DROME (414-710): 2.07e-59: 211: 12.66
+	Hs
		903409 KAT2B_HUMAN (1392-1504): 3.93e-32: 138: 29.20		WDR5_HUMAN (399-710): 1.44e-45: 170: 12.38
+	Hs
		1281459 BAZ1B_HUMAN (1518-1668): 6.99e-28: 125: 19.21		FBXW7_HUMAN (409-747): 3.31e-46: 181: 12.35
+	Hs
		903408 KAT2A_HUMAN (1392-1504): 1.96e-29: 129: 29.20		WDR5_HUMAN (399-710): 1.44e-45: 170: 12.38
+	Mm
		903679 KAT2A_MOUSE (1392-1504): 3.23e-29: 129: 29.20		WDR5_MOUSE (399-710): 1.44e-45: 170: 12.38
+	Hs
		1288368 BAZ2B_HUMAN (1495-1630): 8.27e-32: 139: 27.21		SNR40_HUMAN (28-212): 6.57e-30: 125: 12.63
+	Hs
		1288369 BAZ2A_HUMAN (1506-1631): 4.55e-31: 136: 22.22		SNR40_HUMAN (28-212): 6.57e-30: 125: 12.63