HitPredict

Interactor 1: SYT1 (P21707)
Synaptotagmin-1 (Synaptotagmin I) (SytI) (p65)
Gene: SYT1

Interactor 2: VAMP2 (P63045)
Vesicle-associated membrane protein 2 (VAMP-2) (Synaptobrevin-2)
Gene: VAMP2

Species: Rattus norvegicus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.58 0.60 0.595

The method score is based on:

Property Details
Experiments 20173763, 8567678
Identification Methods fluorescent resonance energy transfer, anti bait coimmunoprecipitation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000149 - SNARE binding
GO:0005516 - calmodulin binding
GO:0005543 - phospholipid binding
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
and 11 others

more...
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 421
Rn

1 116
+ Hs
+ Hs
+ Mm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024