HitPredict

Interactor 1: MK03 (P21708)
Mitogen-activated protein kinase 3 (MAP kinase 3) (MAPK 3) (EC 2.7.11.24) (ERT2) (Extracellular signal-regulated kinase 1) (ERK-1) (Insulin-stimulated MAP2 kinase) (MAP kinase isoform p44) (p44-MAPK) (MNK1) (Microtubule-associated protein 2 kinase) (p44-ERK1)
Gene: Mapk3

Interactor 2: HS71L (P55063)
Heat shock 70 kDa protein 1-like (Heat shock 70 kDa protein 1L) (Heat shock 70 kDa protein 3) (HSP70.3)
Gene: Hspa1l

Species: Rattus norvegicus

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	19935650
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005739 - mitochondrion GO:0005829 - cytosol and 1 others more... GO:0005886 - plasma membrane
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 380 Rn			1 641
+	Hs
		564010 MK03_HUMAN (14-380): 3.23e-157: 448: 97.55		HSP76_HUMAN (1-641): 0: 957: 79.16
+	Rn
		483814 MK03_RAT (1-380): 6.6e-156: 445: 100.00		HS71B_RAT (5-641): 0: 951: 88.58
+	Hs
		503480 MK03_HUMAN (14-380): 3.23e-157: 448: 97.55		HSP7C_HUMAN (4-615): 0: 948: 85.46
+	Rn
		600371 MK03_RAT (1-380): 6.6e-156: 445: 100.00		HSP7C_RAT (4-615): 0: 947: 85.62
+	Rn
		538777 MK03_RAT (1-380): 6.6e-156: 445: 100.00		HSP72_RAT (3-641): 0: 928: 81.28
+	Hs
		504011 MK07_HUMAN (2-373): 2.88e-137: 412: 47.88		HSP7C_HUMAN (4-615): 0: 948: 85.46
+	Hs
		504142 MK14_HUMAN (28-379): 2.67e-140: 404: 46.89		HSP7C_HUMAN (4-615): 0: 948: 85.46