Interactor 1: MK03 (P21708)
Mitogen-activated protein kinase 3 (MAP kinase 3) (MAPK 3) (EC 2.7.11.24) (ERT2) (Extracellular signal-regulated kinase 1) (ERK-1) (Insulin-stimulated MAP2 kinase) (MAP kinase isoform p44) (p44-MAPK) (MNK1) (Microtubule-associated protein 2 kinase) (p44-ERK1)
Gene: Mapk3

Interactor 2: VGFR3 (Q91ZT1)
Vascular endothelial growth factor receptor 3 (VEGFR-3) (EC 2.7.10.1) (Fms-like tyrosine kinase 4) (FLT-4) (Tyrosine-protein kinase receptor FLT4)
Gene: Flt4

Species: Rattus norvegicus

Source: mint

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.33 1.00 0.575

The method score is based on:

Property Details
Experiments 19935650
Identification Methods anti bait coimmunoprecipitation
Interaction Type association

The annotation score is based on:

Property Details
Interacting Pfam domains I-set~Pkinase, PK_Tyr_Ser-Thr~Pkinase
Common GO terms GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0070374 - positive regulation of ERK1 and ERK2 cascade
Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 380
Rn

1 1363
+ Hs
+ Rn
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+ Mm
+ Mm
+ Mm
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Last updated: 15 Jul 2024