HitPredict

Interactor 1: EPHA1 (P21709)
Ephrin type-A receptor 1 (hEpha1) (EC 2.7.10.1) (EPH tyrosine kinase) (EPH tyrosine kinase 1) (Erythropoietin-producing hepatoma receptor) (Tyrosine-protein kinase receptor EPH)
Gene: EPHA1

Interactor 2: PARD3 (Q8TEW0)
Partitioning defective 3 homolog (PAR-3) (PARD-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2-5) (PAR3-alpha)
Gene: PARD3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PDZ~fn3, PDZ~SAM_1
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 976 Hs			1 1356
+	Hs
		1072560 EPHA7_HUMAN (2-975): 0: 1117: 43.22		PARD3_HUMAN (1-1356): 0: 709: 100.00
+	Hs
		872464 EPHA5_HUMAN (3-975): 0: 1117: 41.91		PARD3_HUMAN (1-1356): 0: 709: 100.00
+	Hs
		872679 EPHA4_HUMAN (5-975): 0: 1108: 43.50		PARD3_HUMAN (1-1356): 0: 709: 100.00
+	Hs
		665414 EPHA3_HUMAN (22-975): 0: 1097: 43.01		PARD3_HUMAN (1-1356): 0: 709: 100.00
+	Hs
		665294 EPHA2_HUMAN (24-976): 0: 1056: 49.90		PARD3_HUMAN (1-1356): 0: 709: 100.00
+	Hs
		872669 EPHA4_HUMAN (5-975): 0: 1108: 43.50		MAGI2_HUMAN (68-1181): 1.8e-38: 159: 13.66
+	Hs
		1072546 EPHA7_HUMAN (2-975): 0: 1117: 43.22		LNX2_HUMAN (50-361): 6.83e-21: 101: 11.35
+	Hs
		1020163 EPHA7_HUMAN (2-975): 0: 1117: 43.22		PTN13_HUMAN (39-368): 1.59e-16: 88.1: 12.50
+	Hs
		872431 EPHA5_HUMAN (3-975): 0: 1117: 41.91		PTN13_HUMAN (39-368): 1.59e-16: 88.1: 12.50
+	Hs
		665589 EPHB2_HUMAN (27-975): 0: 1112: 41.01		PTN13_HUMAN (39-368): 1.59e-16: 88.1: 12.50
+	Hs
		872638 EPHA4_HUMAN (5-975): 0: 1108: 43.50		PTN13_HUMAN (39-368): 1.59e-16: 88.1: 12.50
+	Hs
		1072558 EPHA7_HUMAN (2-975): 0: 1117: 43.22		LNX1_HUMAN (73-395): 1.66e-13: 77.4: 12.79
+	Hs
		600564 EPHA1_HUMAN (1-976): 0: 1103: 100.00		PTN13_HUMAN (39-368): 1.59e-16: 88.1: 12.50
+	Hs
		665633 EPHB2_HUMAN (27-975): 0: 1112: 41.01		LNX1_HUMAN (73-395): 1.66e-13: 77.4: 12.79
+	Hs
		872678 EPHA4_HUMAN (5-975): 0: 1108: 43.50		LNX1_HUMAN (73-395): 1.66e-13: 77.4: 12.79
+	Hs
		665393 EPHA3_HUMAN (22-975): 0: 1097: 43.01		PTN13_HUMAN (39-368): 1.59e-16: 88.1: 12.50
+	Hs
		1049958 EPHA7_HUMAN (2-975): 0: 1117: 43.22		SCRIB_HUMAN (66-355): 5.59e-09: 63.1: 12.75
+	Hs
		665600 EPHB2_HUMAN (27-975): 0: 1112: 41.01		SCRIB_HUMAN (66-355): 5.59e-09: 63.1: 12.75
+	Hs
		665228 EPHA2_HUMAN (24-976): 0: 1056: 49.90		PTN13_HUMAN (39-368): 1.59e-16: 88.1: 12.50
+	Hs
		872410 EPHB3_HUMAN (21-975): 0: 1056: 42.93		LNX1_HUMAN (73-395): 1.66e-13: 77.4: 12.79