HitPredict

Interactor 1: C5AR1 (P21730)
C5a anaphylatoxin chemotactic receptor 1 (C5a anaphylatoxin chemotactic receptor) (C5a-R) (C5aR) (CD antigen CD88)
Gene: C5AR1

Interactor 2: ATM (Q13315)
Serine-protein kinase ATM (EC 2.7.11.1) (Ataxia telangiectasia mutated) (A-T mutated)
Gene: ATM

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0007165 - signal transduction
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 350 Hs			1 3056
+	Hs
		723296 APJ_HUMAN (18-343): 3.3e-69: 222: 24.71		ATM_HUMAN (1-3056): 0: 3806: 100.00
+	Hs
		723037 OPRM_HUMAN (1-346): 5.02e-67: 217: 23.03		ATM_HUMAN (1-3056): 0: 3806: 100.00
+	Hs
		895616 CXCR4_HUMAN (6-323): 1.6e-67: 217: 26.24		ATM_HUMAN (1-3056): 0: 3806: 100.00
+	Hs
		598935 FPR1_HUMAN (13-349): 9.02e-67: 215: 30.57		ATM_HUMAN (1-3056): 0: 3806: 100.00
+	Hs
		1031631 C5AR2_HUMAN (2-339): 6.08e-65: 210: 38.71		ATM_HUMAN (1-3056): 0: 3806: 100.00
+	Hs
		1031594 LPAR4_HUMAN (43-308): 1.01e-25: 107: 29.50		ATM_HUMAN (1-3056): 0: 3806: 100.00
+	Hs
		723038 OPRM_HUMAN (1-346): 5.02e-67: 217: 23.03		ATR_HUMAN (1223-3056): 0: 1214: 20.34
+	Hs
		787552 CML1_HUMAN (3-348): 1.08e-77: 244: 32.51		MTOR_HUMAN (1846-3055): 0: 843: 16.65
+	Hs
		723279 APJ_HUMAN (18-343): 3.3e-69: 222: 24.71		MTOR_HUMAN (1846-3055): 0: 843: 16.65
+	Hs
		787434 CXCR4_HUMAN (6-323): 1.6e-67: 217: 26.24		MTOR_HUMAN (1846-3055): 0: 843: 16.65
+	Hs
		598924 FPR1_HUMAN (13-349): 9.02e-67: 215: 30.57		MTOR_HUMAN (1846-3055): 0: 843: 16.65
+	Hs
		429015 ADRB2_HUMAN (42-346): 7.28e-71: 228: 17.65		PRKDC_HUMAN (2005-3056): 6.86e-155: 545: 17.20
+	Hs
		598934 FPR1_HUMAN (13-349): 9.02e-67: 215: 30.57		PRKDC_HUMAN (2005-3056): 6.86e-155: 545: 17.20
+	Hs
		944388 LPAR4_HUMAN (43-308): 1.01e-25: 107: 29.50		PRKDC_HUMAN (2005-3056): 6.86e-155: 545: 17.20
+	Hs
		787363 CXCR4_HUMAN (6-323): 1.6e-67: 217: 26.24		PK3CB_HUMAN (2385-3011): 9.82e-99: 348: 13.76
+	Hs
		822537 CXCR4_HUMAN (6-323): 1.6e-67: 217: 26.24		PK3CG_HUMAN (2437-2965): 4.25e-88: 316: 16.14
+	Mm
		936867 CXCR4_MOUSE (6-323): 4.98e-68: 219: 25.99		PK3CG_MOUSE (2446-2965): 4.69e-87: 313: 16.04