HitPredict

Interactor 1: FGFR2 (P21802)
Fibroblast growth factor receptor 2 (FGFR-2) (EC 2.7.10.1) (K-sam) (KGFR) (Keratinocyte growth factor receptor) (CD antigen CD332)
Gene: FGFR2

Interactor 2: FANCI (Q9NVI1)
Fanconi anemia group I protein (Protein FACI)
Gene: FANCI

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.500

Property	Details
Experiments	35384245
Identification Methods	affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0016020 - membrane
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 821 Hs			1 1328
+	Hs
		508224 FGFR1_HUMAN (1-820): 0: 772: 71.17		FANCI_HUMAN (1-1322): 0: 1947: 100.00
+	Hs
		609573 FGFR3_HUMAN (10-821): 0: 731: 65.69		FANCI_HUMAN (1-1322): 0: 1947: 100.00
+	Hs
		665668 EPHB2_HUMAN (9-766): 1.95e-166: 511: 17.58		FANCI_HUMAN (1-1322): 0: 1947: 100.00
+	Hs
		872719 EPHA4_HUMAN (18-794): 4.37e-165: 506: 18.60		FANCI_HUMAN (1-1322): 0: 1947: 100.00
+	Hs
		674543 UFO_HUMAN (5-818): 3.59e-160: 490: 22.49		FANCI_HUMAN (1-1322): 0: 1947: 100.00
+	Hs
		1081622 NTRK3_HUMAN (166-765): 7.85e-160: 488: 25.31		FANCI_HUMAN (1-1322): 0: 1947: 100.00
+	Hs
		385601 NTRK1_HUMAN (157-765): 4.6e-143: 443: 25.04		FANCI_HUMAN (1-1322): 0: 1947: 100.00
+	Hs
		738279 FLT3_HUMAN (342-800): 5.44e-85: 293: 36.15		FANCI_HUMAN (1-1322): 0: 1947: 100.00
+	Hs
		729368 VGFR3_HUMAN (42-385): 5.85e-18: 91.4: 17.62		FANCI_HUMAN (1-1322): 0: 1947: 100.00
+	Hs
		987299 TYRO3_HUMAN (167-367): 4.11e-12: 72.1: 22.55		FANCI_HUMAN (1-1322): 0: 1947: 100.00
+	Hs
		572690 VGFR1_HUMAN (5-134): 1.03e-11: 70.9: 16.42		FANCI_HUMAN (1-1322): 0: 1947: 100.00